Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (45) GO Terms (10) Nucleotides (358) Proteins (35) Interactants (652) Wiki
XB-GENEPAGE- 478451

Gene Symbol: crx

Gene Name: cone-rod homeobox

Synonyms: otx5 , Xotx5 , Xotx5b , otx5b , crx-a , crx-b
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:
Transcription factor involved in anterior and eye development. Promotes the differentiation of both rod and cone photoreceptors cells in the retina. Together with other retinal homeobox proteins, acts ...[+]


Interactants: YYY

OMIM Disease Associations: CONE-ROD DYSTROPHY 2; CORD2 [+]
1/5
 
Xenbase Gene ID XB-GENE-478452 XB-GENE-865179 XB-GENE-6252876
Gene Symbol crx crx.L crx.S
Chromosome scaffold_8 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.2944 [+] Xl.511 Xl.42160
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 72 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine crx crx.L crx.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CRX OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Crx MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN crx ZFIN Ensembl
chicken
fruit fly
worm
WORMBASE
Publications
First: Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning. [Mech Dev 1998]
Most recent: Activation of a T-box-Otx2-Gsc gene network independent of TBP and TBP-related factors. [Development 2016]
View All Papers 6 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 10 terms 9 terms
EC
PANTHER crx
KEGG Pathways K09326 K09326 K18490
KOG [K] Homeobox transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Crx Ab1 Crx Ab1 Crx Ab1
ORF crx ORF1 crx ORF2
Affymetrix 1.0 Str.2944.1.S1_at [+] Xl.511.1.S1_at Xl.917.1.S1_at [+]
Affymetrix 2.0 Xl2.511.2.S1_a_at [+] Xl2.42160.1.S2_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556