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Summary Expression Gene Literature (23) GO Terms (9) Nucleotides (106) Proteins (27) Interactants (409) Wiki
XB-GENEPAGE- 479143

Gene Symbol: lmo2

Gene Name: LIM domain only 2

Synonyms: LMO-2 , xlmo2 , xlmo-2
Add Xenopus synonyms , Nomenclature history


Gene Function: transcription factor

Protein Function:
Transcription factor that acts synergistically with tal1/scl and gata1 to specify embryonic dorsal mesoderm to a hematopoietic fate. Induces globin gene expression together with fgf.


Interactants: YYY

OMIM Disease Associations:
1/7
 
Xenbase Gene ID XB-GENE-479144 XB-GENE-17336858 XB-GENE-6254426
Gene Symbol lmo2 lmo2.L lmo2.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.14577 [+] Xl.9549 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 46 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine lmo2 lmo2.L lmo2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LMO2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Lmo2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN lmo2 ZFIN Ensembl
chicken
GEISHA LMO2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Genomic structure, alternative transcripts and chromosome location of the human LIM domain binding protein 1 gene LDB1. [Cytogenet Cell Genet 1999]
Most recent: Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage. [Proc Natl Acad Sci U S A 2017]
View All Papers 10 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 2 terms 4 terms
EC
PANTHER lmo2
KEGG Pathways K15612 K15612 K15612
KOG [R] Transcription factor, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Lmo2 Ab1 Lmo2 Ab1
Transgene Tg(lmo2:Katushka;cryga:GFP) Tg(lmo2:Katushka;cryga:GFP) Tg(lmo2:Katushka;cryga:GFP)
ORF lmo2 ORF1
Affymetrix 1.0 StrJgi.1351.1.S1_at [+] Xl.9549.1.S1_at [+]
Affymetrix 2.0 Xl2.9549.1.S1_at [+]

Symbol legend[+]

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