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Summary Expression Gene Literature (46) GO Terms (13) Nucleotides (478) Proteins (51) Interactants (965) Wiki
XB-GENEPAGE-6258352
Gene Symbol: col2a1

Gene Name: collagen, type II, alpha 1

Synonyms: col11a3 , xcol2a1 , X-col II , col2a1-a , col2a1-b ( Add synonyms , Nomenclature history )

Gene Function:

Protein Function :
Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive fo...[+]


Interactants: Loading ...
Disease Ontology: otospondylomegaepiphyseal dysplasia [+]

OMIM Diseases: COLLAGEN, TYPE II, ALPHA-1; COL2A1 [+]

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Xenbase Gene ID XB-GENE-6258353 XB-GENE-6252613 XB-GENE-6252612
Gene Symbol col2a1 col2a1.L col2a1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 394828
Entrez Gene: 397738
Entrez Gene: 397739
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL Swiss-Prot RefSeq TrEMBL Swiss-Prot RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine col2a1 col2a1.L col2a1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
COL2A1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Col2a1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR col2a1a col2a1b ZFIN Ensembl
chicken
GEISHA COL2A1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Expression of two nonallelic type II procollagen genes during Xenopus laevis embryogenesis is characterized by stage-specific production of alternatively spliced transcripts., J Cell Biol 1991                  
Most Recent Mechanistic insights from the LHX1-driven molecular network in building the embryonic head., Dev Growth Differ 2019  
All View All Papers 3 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 4 terms 3 terms
PANTHER col2a1
KEGG Pathways K19719 K19719 K19719
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon Horizon
Antibody Col2a1 Ab1 , Col2a1 Ab2 Col1a1 Ab1 , Col2a1 Ab1 , Col2a1 Ab2 Col1a1 Ab1 , Col2a1 Ab1 , Col2a1 Ab2
ORF col2a1.L ORF1 col2a1.S ORF1
Affymetrix 1.0 Str.51515.1.S1_at [+] Xl.606.1.S1_s_at Xl.1286.1.S2_at [+]
Affymetrix 2.0 Xl2.606.1.S1_s_at Xl2.1286.1.S1_s_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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