Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (8) GO Terms (6) Nucleotides (57) Proteins (22) Interactants (107) Wiki
XB-GENEPAGE-6453898
Gene Symbol:
brca2

Gene Name:
BRCA2, DNA repair associated

Synonyms:
fad , facd , fad1 , brcc2 , fancb , fancd1 , brovca2 , breast cancer 2 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
medulloblastoma [+]

OMIM:
MEDULLOBLASTOMA; MDB [+]

External Links:
 
Xenbase Gene ID XB-GENE-6453899 XB-GENE-6486713 XB-GENE-17342247
Gene Symbol brca2 brca2.L brca2.S
Chromosome Chr02 chr2L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100038818
108708691
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine brca2 brca2.L brca2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BRCA2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Brca2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Brca2 Ensembl
zebrafish
ZFIN, AGR brca2 ZFIN Ensembl
chicken
GEISHA BRCA2 Ensembl
fruit fly
FLYBASE Brca2 Ensembl
worm
Publications
First Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation., J Med Genet 2004  
Most Recent HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair., Nucleic Acids Res 2020  
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 1 terms 0 term
PANTHER brca2
KEGG Pathways K08775
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks brca2
Antibodies Brca2 Ab1 Brca2 Ab1 Brca2 Ab1
Clones Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556