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XB-GENEPAGE-6455903
Gene Symbol:
irs2
Gene Name: insulin receptor substrate 2
Synonyms:
irsu
( Gene Function: RNA polymerase II, large subunit Protein Function
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May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidyl...[+]
Interactants:
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Diseases: Disease Ontology:
type 2 diabetes mellitus
OMIM:
TYPE 2 DIABETES MELLITUS; T2D
External Links:
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Xenbase Gene ID | XB-GENE-6455904 | XB-GENE-17346586 | XB-GENE-17346587 | |||||
Gene Symbol | irs2 | irs2.L | irs2.S | Chromosome | Chr3 | chr3L | ||
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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CDS |
Gene model
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Gene model
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Entrez Gene |
394823
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108711802
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | irs2 | irs2.L | irs2.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Opposite T3 Response of ACTG1-FOS Subnetwork Differentiate Tailfin Fate in Xenopus Tadpole and Post-hatching Axolotl., Front Endocrinol (Lausanne) 2019 ![]() |
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Most Recent |
Opposite T3 Response of ACTG1-FOS Subnetwork Differentiate Tailfin Fate in Xenopus Tadpole and Post-hatching Axolotl., Front Endocrinol (Lausanne) 2019 ![]() |
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All | View All Papers | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 11 terms | 2 terms | 0 term | |||||
PANTHER | irs2 | |||||||
KEGG Pathways | K16172 | |||||||
KOG |
[K] RNA polymerase II, large subunit
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | irs2 | |||||||
Clones | Horizon Source BioScience | Horizon | ||||||
Plasmids | Addgene | Addgene |
Symbol legend:



