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Summary Expression Gene Literature (7) GO Terms (8) Nucleotides (291) Proteins (23) Interactants (221) Wiki
XB-GENEPAGE- 971938

Gene Symbol: lmo4.1

Gene Name: LIM domain only 4, gene 1

Synonyms: Xlmo4
Add Xenopus synonyms , Nomenclature history


Gene Function: Transcription factor, contains HOX domain

Protein Function:
Acts as a positive cofactor of GATA transcription factors to establish the identity of the ventral mesoderm during gastrulation. Down-regulation in the dorsal mesoderm is necessary for the proper forma...[+]


Interactants: Loading ...

OMIM Disease Associations:
1/5
 
Xenbase Gene ID XB-GENE-971939 XB-GENE-17343300 XB-GENE-6486208
Gene Symbol lmo4.1 lmo4.1.L lmo4.1.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.145 Xl.30807 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 47 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine lmo4.1 lmo4.1.L lmo4.1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LMO4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Lmo4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN lmo4a ZFIN Ensembl
chicken
GEISHA LMO4 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Xenopus Xlmo4 is a GATA cofactor during ventral mesoderm formation and regulates Ldb1 availability at the dorsal mesoderm and the neural plate. [Dev Biol 2003]
Most recent: Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis. [Proc Natl Acad Sci U S A 2017]
View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 0 term 2 terms
EC
PANTHER lmo4.1
KEGG Pathways
KOG [R] Transcription factor, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF lmo4.1 ORF1
Affymetrix 1.0 Str.145.1.S1_at [+] Xl.24588.2.S1_a_at [+]
Affymetrix 2.0 Xl2.24588.1.S1_at [+]

Symbol legend[+]

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