[provisional- machine annotated only] Gene Symbol: wee1 [Predicted: Source is Human Entrez Gene] Gene Name: WEE1 homolog [Predicted: Source is Human Entrez Gene] Synonyms: wee1a Add Xenopus synonyms Gene Function: Interactants: cdk1(50) , pold1(30) , cdc25c(21) , myt1(20) , ccnb1.2(18) , rasgrf1(17) , wee2(9) View All

Molecules		tropicalis	laevis
Gene			JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001126965|Xenopus (Silurana) tropicalis uncharacterized LOC100145524 (LOC100145524), mRNA AGAGCTTGGGGGGGACGCGCAGGGCCCGGTGTGTTTGTGCGTGTAGGAGCGGCCCCGCCTCTGGGTGTAACCGTGTCACTGGCCGTCGGTACCGCTGTCACTTTCTACCGCTCCCGCCTAGGCCCCGGGGCCTGGATAATGCTCTCCGGCCCAGCCGCTGCCTTCCTACCGAGGATAGTTCCGCGATGAGCGCCCGTGTTTCGCCGTCTCAGCCGCCCCGGACTATGAGCCTCCAGCCCGTTCGCCACAAGCTGTTCTTCAGCGACACGGAGGAGGAAGAGGACGGGCACAGCACCGGGGAGGACTCGGCCTTCCAGGAGAGTGACTCGCCCGTATCCGGGCTGCGAGGGGGGCCCACAGCCAAGCCAGAGGGGAGGCCGCCGGGGGGCTCCTGGGAAGAGGAGGAGGAAGAGGAAGGAATCGGATCGTCTCCGATCAAATCGCCCGGCGATTATTTTATGAGCGGCTCCCCGACTTACCGAGAACTGGCTCCCGAGTCCCCTGCCGGGTACGGCTCCCGATCCCCCCAGGGCCCCGGCTCCCCCATCCCCGAGTGCCCCGGCACCCCGCCCCACAAGACTTTCCGCAAACTCCGGCTCTTCGACACCCCGCACACCCCCAAGAGTTTACTGTCGAAAGCTCGGGGAATCGGTTCCAGCGCCTTGAGGTTCCGAGGCGGGTCGCTGTTCCGGGAAGCCGAGAAGGTTCCAAAGCCAGAGTTTGTGTACAGCACCCCTCAGGTCAACATCAACCCCTTCACCCCCGATTCCTTGGAAATCCAGTCGTCCACCGGGCTTTGTCGCAGGAGAAAAAGGGCACTACTAAATGACTCTTGTGGGGAAGACATGGAAGGCAGCGACTGCGAGCTGGAAGACGATGACATTCGCCCGGCAAAGCGGATCCCAATAACGGAAAGCAACATGAAGTCTCGCTATGCGACCGAGTTCCACGAATTGGAGAAAATCGGTTCCGGCGAGTTCGGCTCCGTGTTCAAATGCGTGAAGAGGCTCGACGGTTGCATCTATGCCATAAAGCGCTCCAAGAAGCCCCTGGCCGGCTCTGTTGATGAACAGAATGCATTGAGGGAGGTGTATGCGCACGCAGTGCTTGGGCAGCACCCCCACGTAGTCCGATACTACTCTGCCTGGGCGGAAGACGACCATATGCTTATTCAGAATGAGCATTGTAATGGCGGGAGTCTAGCCGACGCTATCAGTGAGAATTACAGGACGATGCAGTTTTTCTCTGAGCCGGAACTCAAGGATCTACTTTTGCAAGTAGCTCGGGGCCTGAAATATATTCACTCCATGTCATTGGTGCATATGGACATAAAGCCCAGTAACATATTCATATCGCGGACGACCGTCCCAAACACAGCGGTTGAAGAAGGGGATGATGAGGACTGCGGCTCCAGAAAAGTTATATATAAAATAGGGGATCTTGGTCACGTGACCAGAGTCTCCAGTCCCCAAGTGGAAGAAGGCGACAGTCGATTTCTTGCCAATGAAGTCTTACAAGAGGATTACACGCACTTGCCCAAAGCAGATATATTTGCCCTGGCGCTGACAGTGTGGTGCGCAGCTGGAGCGGAGCCCCTTCCGACCAATGGAGAGCAGTGGCACGAGATCCGGCAGGGCAAGCTCCCGCGGGTGCCCCAGTCGCTCTCACTAGAGTTTATGGACTTGATCAAGCTTATGATTTCTCCCGATCCGGAGAAAAGGCCTTCGTCCGTGGCCCTGGTGAAGCATTCCGTTCTCCTGTCCGCGTCCCGGAAAAGCGCCGAGCAGCTGCGGATAGAACTCAACGCGGAGAAATTTAAAAACGCACTTTTGCAGAAGGAACTAAAGAAAGCACAAATAGCAAAAGCAGCAGCGGAGGAAAGAGCCCTCTTCCCCGACCGAGTAGTGACGCGATCGACGGCTCAGAACAACCGGACGACCCGCCTCATCGGGAAGAAGATGAACCGATCCGTCAGCCTTACTATATACTGACATATAGTACAGCCTCGTTGCAATCGCAAAAAAAAAAAAAAA	Refseq >NM_001090717|Xenopus laevis Wee1B kinase (wee1B), mRNA ATGAACGTCCAGCCCCGGAATATGAACGTCCAGCCCCGGAATATGAACGTCCAGCCCGTGCGCCACAAGCTCTTCTTCAGCGACACAGACGAGGAGGAGGAGGACGGACACAGCACCGGGGAGGACTCGGCTTTTCAAGAGAGCGACTCGCCCGTGTCCCGGCAGAGAGAGAAGCAGGAAGGGAAGCCGCCGGGAGGCACCTGGGAGGAGTTGGAGGAGGAGGAAGGGTTCGGATCGTCTCCCATCAAATCGCCCGGGGATTTCTTCATGAGCGACTCCCCGTCCTACCGGCAACTGGCTCCCGCCTCCCCCACCCGATCCCCCCAAGGACCCACATCCCCCATCCCCGAGTGCCCCGGGACCCCGCCCCACAAGACTTTCCGCAAGCTCCGCCTCTTCGACACCCCGCACACCCCCAAGAGTTTATTGTCGAAAGCTCGAGGAATCGGCTCGAGCGCATTGAGGTTTCGAGGCGGGACGCTATTCCGAGAAGCGGAGAAGGCTCCAAAGCCAGAGTTTGTGTACAGCACCCCTCAGGTCAACATCAACCCCTTCACCCCGGATTCCTTGGAAATCCAGTCTTCTGCCGGGCTTTGTCGCGGGAGAAAAAGGGCACTTTTAAATGACTCCTGTGGGGAAGACATGGAAGGCAGCGACTGTGAACTGGAAGATGAAGACATCCGGCCCGCGAAGCGGATCCCAATAACAGAAAGCAACATGAAGTCTCGATACGCAACAGAATTCCATGAACTGGAGAAAATCGGTTCCGGAGAATTCGGCTCTGTGTTTAAATGCGTGAAGAGACTCGATGGCTGCATCTACGCCATAAAGCGATCGAAGAAGCCCCTTGCCGGCTCTGTGGATGAGCAGAATGCTTTGAGAGAGGTGTATGCACACGCTGTATTGGGACAGCACCCCCATGTGGTCCGATACTACTCCGCTTGGGCAGAAGATGACCACATGCTCATTCAGAATGAGTATTGTAATGGCGGGAGCTTGTCTGATGTCATCAGTGAGAATTACAGGACGATGCAATATTTCACGGAGCCAGAATTAAAGGATTTGCTCTTGCAAGTGGCTCGCGGCCTGAAATATATTCACTCCATGTCACTGGTGCACATGGACATAAAGCCGAGTAACATATTCATATCAAGGACGACCCTCCCAAACACGGCAGTCGAAGAAGCGGACGATGAGGAATGTGGCTCCGGAAAAGTAATCTATAAAATAGGTGATCTTGGTCACGTAACAAGAGTCTCCAGTCCCCAAGTGGAAGAAGGTGACAGTCGGTTTCTTGCCAATGAAGTGCTACAGGAGAACTATACCCACTTGGCAAAAGCTGATATATTTGCCCTGGCGCTGACAGTGTGGAGCGCAGCGGGAGCAGAGCCCTTTCCTACCAATGGAGACCAGTGGCACGAGATCAGACAGGGCAAGCTGCCCCGGGTGCCACAGTTACTCTCTCAAGAGTTTGTGGACTTAATCAAGCTTATGATTTCACCCGATCCAGAGAAAAGGCCTTCGTCCGTGGCCCTGGTCAAGCATTCCGTTCTCCTATCCGCGTCTCGCAAGAGCGCCGAGCAGCTGCGCATAGAACTCGATGCCGAGAAGTTTAAAAATGCACTTCTGCAGAAGGAACTGAAGAAAGCACAAATAGCCAAAGCAGCGGCAGAGGAACGAGCCCATTTCCCCGACCGGATAGCGACTCGATCCACGACTCAGAACAACCGGACGACCCGCCTCATCGGGAAGAAGATGAACCGATCCGTCAGCCTCACTATATACTGA
Protein		Refseq >NP_001120437|uncharacterized protein LOC100145524 [Xenopus (Silurana) tropicalis] MSARVSPSQPPRTMSLQPVRHKLFFSDTEEEEDGHSTGEDSAFQESDSPVSGLRGGPTAKPEGRPPGGSWEEEEEEEGIGSSPIKSPGDYFMSGSPTYRELAPESPAGYGSRSPQGPGSPIPECPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIGSSALRFRGGSLFREAEKVPKPEFVYSTPQVNINPFTPDSLEIQSSTGLCRRRKRALLNDSCGEDMEGSDCELEDDDIRPAKRIPITESNMKSRYATEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPHVVRYYSAWAEDDHMLIQNEHCNGGSLADAISENYRTMQFFSEPELKDLLLQVARGLKYIHSMSLVHMDIKPSNIFISRTTVPNTAVEEGDDEDCGSRKVIYKIGDLGHVTRVSSPQVEEGDSRFLANEVLQEDYTHLPKADIFALALTVWCAAGAEPLPTNGEQWHEIRQGKLPRVPQSLSLEFMDLIKLMISPDPEKRPSSVALVKHSVLLSASRKSAEQLRIELNAEKFKNALLQKELKKAQIAKAAAEERALFPDRVVTRSTAQNNRTTRLIGKKMNRSVSLTIY	Refseq >NP_001084186|wee1-like protein kinase 1-B [Xenopus laevis] MNVQPRNMNVQPRNMNVQPVRHKLFFSDTDEEEEDGHSTGEDSAFQESDSPVSRQREKQEGKPPGGTWEELEEEEGFGSSPIKSPGDFFMSDSPSYRQLAPASPTRSPQGPTSPIPECPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIGSSALRFRGGTLFREAEKAPKPEFVYSTPQVNINPFTPDSLEIQSSAGLCRGRKRALLNDSCGEDMEGSDCELEDEDIRPAKRIPITESNMKSRYATEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPHVVRYYSAWAEDDHMLIQNEYCNGGSLSDVISENYRTMQYFTEPELKDLLLQVARGLKYIHSMSLVHMDIKPSNIFISRTTLPNTAVEEADDEECGSGKVIYKIGDLGHVTRVSSPQVEEGDSRFLANEVLQENYTHLAKADIFALALTVWSAAGAEPFPTNGDQWHEIRQGKLPRVPQLLSQEFVDLIKLMISPDPEKRPSSVALVKHSVLLSASRKSAEQLRIELDAEKFKNALLQKELKKAQIAKAAAEERAHFPDRIATRSTTQNNRTTRLIGKKMNRSVSLTIY UniProtKB

Genomic		tropicalis
Genome Browser					Xenbase
Synteny

Expression		tropicalis	laevis
UniGene		Str.38464	[+] Xl.9986
Unigene EST Profile		EST Profile
GEO data			GEO
Images		1 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	WEE1
mouse		MGI	Wee1	All(4) Gene Trapped(1) Targeted, other(1) Targeted, knock Out(1)
zebrafish		ZFIN	wee1	3 Lines(s)

Publications
First:		Regulation of the G2-mitosis transition. [Biochem Cell Biol 1992]
Most recent:		Ser 15 of WEE1B is a potential PKA phosphorylation target in G2/M transition in one-cell stage mouse embryos. [Mol Med Rep 2013]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Str.38464.1.S1_at	Xl.17393.1.S1_at [+] Xl.9986.1.A1_at
Affymetrix 2.0			Xl2.17393.1.S2_at [+] Xl2.9986.1.A1_at

Symbol legend[+]

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   - Literature Or Expression Images