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Summary Expression Gene Literature (160) GO Terms (5) Nucleotides (904) Proteins (29) Interactants (236) Wiki
XB-GENEPAGE-852770
Gene Symbol:
sftpc

Gene Name:
surfactant, pulmonary-associated protein C

Synonyms:
SP-C , xSP-C , SPC , surfc ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
idiopathic pulmonary fibrosis [+]

OMIM:
SURFACTANT METABOLISM DYSFUNCTION, PULMONARY, 1; SMDP1 [+]

External Links:
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Xenbase Gene ID XB-GENE-852771 XB-GENE-17346349 XB-GENE-6489007
Gene Symbol sftpc sftpc.L sftpc.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100038236
108711616
779071
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sftpc sftpc.L sftpc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SFTPC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sftpc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sftpc Ensembl
zebrafish
chicken
GEISHA SFTPC Ensembl
fruit fly
worm
Publications
First The G-protein-coupled receptors GPR3 and GPR12 are involved in cAMP signaling and maintenance of meiotic arrest in rodent oocytes., Dev Biol 2005  
Most Recent Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome., Hum Mol Genet 2020                    
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 5 terms 4 terms 4 terms
PANTHER sftpc
KEGG Pathways
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sftpc
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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