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Summary Expression Gene Literature (1101) GO Terms (28) Nucleotides (341) Proteins (51) Interactants (1126) Wiki
XB-GENEPAGE-853081
Gene Symbol:
aurka

Gene Name:
aurora kinase A

Synonyms:
Aurora-A , btak , stk15 , Aurora A , aik , ark1 , aura , stk6 , stk7 , aurora2 , pEg2 , Eg2 , aur-a ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in va...[+]


InterPro :
Aur , Kinase-like dom sf , Protein kinase ATP BS , Ser/Thr kinase AS [+]

Interactants:
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Diseases: 


Disease Ontology:
colorectal cancer

OMIM:
COLORECTAL CANCER; CRC

External Links:
 
Xenbase Gene ID XB-GENE-853082 XB-GENE-866460 XB-GENE-17337404
Gene Symbol aurka aurka.L aurka.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549324
397925
398349
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine aurka aurka.L aurka.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tegg021k02      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards AURKA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Aurka MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Aurka Ensembl
zebrafish
ZFIN, AGR aurka ZFIN Ensembl
chicken
GEISHA AURKB Ensembl
fruit fly
worm
Publications
First Degradation of a developmentally regulated mRNA in Xenopus embryos is controlled by the 3'' region and requires the translation of another maternal mRNA., Mol Cell Biol 1991  
Most Recent Transcriptomic analysis identifies early cellular and molecular events by which estrogen disrupts testis differentiation and causes feminization in Xenopus laevis., Aquat Toxicol 2020  
All View All Papers 3 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 17 terms 15 terms
PANTHER aurka
KEGG Pathways K11481 K11481 K11481
KOG [D] Serine/threonine protein kinase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks aurka
Antibodies Aurka Ab1 , Aurka Ab2 , Aurka Ab3 , Aurka Ab4 , aurka/b Ab1 Aurka Ab1 , Aurka Ab2 , Aurka Ab3 , Aurka Ab4 , aurka/b Ab1 aurka/b Ab1
Morpholinos aurka MO1 aurka MO1 aurka MO1
ORFs aurka.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list