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Summary Expression Gene Literature (1508) GO Terms (11) Nucleotides (73) Proteins (32) Interactants (1325) Wiki
XB-GENEPAGE-853289
Gene Symbol:
egr2

Gene Name:
early growth response 2 (Krox-20 homolog)

Synonyms:
XKr20 , EGR-2 , Krox-20 , XKrox-20 , krox20 ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger transcription factor

Protein Function :
Sequence-specific DNA-binding transcription factor.


InterPro :
PH 9 , Spectrin/alpha-actinin , CH-domain , Actinin actin-bd CS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Charcot-Marie-Tooth disease type 3 [+]

OMIM:
CHARCOT-MARIE-TOOTH DISEASE, DEMYELINATING, TYPE 1D; CMT1D [+]

External Links:
1/3
 
Xenbase Gene ID XB-GENE-853290 XB-GENE-866474 XB-GENE-17340379
Gene Symbol egr2 egr2.L egr2.S
Chromosome Chr7 chr7L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100101746
378520
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine egr2 egr2.L egr2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards EGR2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Egr2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Egr2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR egr2b egr2a ZFIN Ensembl
chicken
GEISHA EGR2 Ensembl
fruit fly
worm
Publications
First Conserved segmental expression of Krox-20 in the vertebrate hindbrain and its relationship to lineage restriction., Development 1991          
Most Recent Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway., Sci Rep 2020              
All View All Papers 89 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 3 terms 0 term
PANTHER egr2
KEGG Pathways K12496 K12496
KOG [R] FOG: Zn-finger
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks egr2
ORFs egr2 ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list