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Summary Expression Gene Literature (14) GO Terms (17) Nucleotides (143) Proteins (39) Interactants (356) Wiki
XB-GENEPAGE-853379
Gene Symbol:
setdb1

Gene Name:
SET domain bifurcated 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
histone methyl transferase

Protein Function :
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, C...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-853380 XB-GENE-866480 XB-GENE-17337298
Gene Symbol setdb1 setdb1.L setdb1.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100490309
432147
108700333
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein Uniprot RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine setdb1 setdb1.L setdb1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SETDB1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Setdb1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Setdb1 Ensembl
zebrafish
ZFIN, AGR setdb1a setdb1b ZFIN Ensembl
chicken
GEISHA MLLT11 Ensembl
fruit fly
worm
Publications
First Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., J Biol Chem 2017          
Most Recent Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., J Biol Chem 2017          
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 9 terms 6 terms
PANTHER setdb1
KEGG Pathways K11421 K11421
KOG [B] Predicted histone methyl transferase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks setdb1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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