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Summary Expression Gene Literature (3) GO Terms (18) Nucleotides (179) Proteins (56) Interactants (79) Wiki
XB-GENEPAGE-854130
Gene Symbol:
rnf111

Gene Name:
ring finger protein 111

Synonyms:
Arkadia , rnf111-b , rnf111-a ( Add synonyms , Nomenclature history )

Gene Function:
mediator of ubiquitin ligase activity

Protein Function :
E3 ubiquitin-protein ligase required for mesoderm patterning during embryonic development. Acts as an enhancer of the transcriptional responses of the smad2/smad3 effectors, which are activated downstr...[+]


InterPro :
Znf RING , Znf RING/FYVE/PHD , RNF111 N , Ig-like fold [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-854131 XB-GENE-854138 XB-GENE-6251809
Gene Symbol rnf111 rnf111.L rnf111.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 780266
447448
779113
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine rnf111 rnf111.L rnf111.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards RNF111 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Rnf111 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Rnf111 Ensembl
zebrafish
rnf111 Ensembl
chicken
GEISHA RNF111 Ensembl
fruit fly
Publications
First Arkadia enhances nodal-related signalling to induce mesendoderm., Nature 2001    
Most Recent Vertebrate development: Et in Arkadia., Curr Biol 2001  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 8 terms 7 terms
PANTHER rnf111
KEGG Pathways K10635 K10635 K10635
KOG [O] FOG: Predicted E3 ubiquitin ligase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks rnf111
ORFs rnf111.L ORF1 rnf111 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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