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Summary Expression Gene Literature (43) GO Terms (17) Nucleotides (138) Proteins (35) Interactants (268) Wiki
XB-GENEPAGE-855790
Gene Symbol:
appl1

Gene Name:
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

Synonyms:
appl , dip13alpha ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction

Protein Function :



Interactants:
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Diseases: 


Disease Ontology:
maturity-onset diabetes of the young

OMIM:
MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 14; MODY14

External Links:
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Xenbase Gene ID XB-GENE-855791 XB-GENE-866622 XB-GENE-17337320
Gene Symbol appl1 appl1.L appl1.S
Chromosome Chr4 Scaffold24 Scaffold40
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100038055
398984
398493
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine appl1 appl1.L appl1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards APPL1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Appl1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Appl1 Ensembl
zebrafish
appl1 Ensembl
chicken
GEISHA APPL1 Ensembl
fruit fly
worm
Publications
First Fixation of the unmethylated or the 5''-CCGG-3'' methylated adenovirus late E2A promoter-cat gene construct in the genome of hamster cells: gene expression and stability of methylation patterns., J Virol 1987  
Most Recent Membrane progesterone receptor induces meiosis in Xenopus oocytes through endocytosis into signaling endosomes and interaction with APPL1 and Akt2., PLoS Biol 2020            
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 6 terms 0 term
PANTHER appl1
KEGG Pathways K08733
KOG [T] Putative GTPase activating proteins (GAPs)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks appl1
ORFs appl1.L ORF1 appl1.S ORF1
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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