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Summary Expression Gene Literature (36) GO Terms (4) Nucleotides (57) Proteins (9) Interactants (429) Wiki
XB-GENEPAGE-855943
Gene Symbol:
h2axl

Gene Name:
H2A.X variant histone-like

Synonyms:
h2a/x , h2a.x , h2afxl ( Add synonyms , Nomenclature history )

Gene Function:
chromatin structure

Protein Function :
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central ro...[+]


Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-22066268 XB-GENE-17331618 XB-GENE-6493983
Gene Symbol h2axl h2axl.L h2ax.lS
Chromosome Scaffold20
Molecules tropicalis laevis.L laevis.S
Genomic Sequence
CDS Gene model
Entrez Gene 734746
mRNA RefSeq
Protein RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine h2axl h2axl.L h2ax.lS
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards H2AX OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR H2ax MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
zebrafish
ZFIN, AGR h2ax ZFIN Ensembl
chicken
GEISHA H2AFX Ensembl
fruit fly
worm
Publications
First DNA-dependent phosphorylation of histone H2A.X during nucleosome assembly in Xenopus laevis oocytes: involvement of protein phosphorylation in nucleosome spacing., EMBO J 1991  
Most Recent Nuclear ARP2/3 drives DNA break clustering for homology-directed repair., Nature 2018                                
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 0 term terms
PANTHER h2axl
KEGG Pathways K11251
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks
Antibodies H2afx Ab1 , H2afx Ab2 H2afx Ab1 , H2afx Ab2 , Hist1h4a Ab4
ORFs h2afx.L ORF1
Clones Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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