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Summary Expression Gene Literature (142) GO Terms (22) Nucleotides (220) Proteins (23) Interactants (1167) Wiki
XB-GENEPAGE- 481981

Gene Symbol: zic1

Gene Name: Zic family member 1

Synonyms: Zic-r1 , opl , odd-paired-like , Zinc finger protein of the cerebellum 1 , Zic-related-1
Add Xenopus synonyms , Nomenclature history


Gene Function: zinc finger, C2H2 type

Protein Function :
Transcriptional activator that induces expression of multiple genes including pax3, en2, snai2/slug, feb and a subset of wnt genes. Has multiple key roles in the regulation of neural induction and neur...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
   CRANIOSYNOSTOSIS 6; CRS6
1/5
 

Xenbase Gene ID XB-GENE-481982 XB-GENE-17336404 XB-GENE-864815
Gene Symbol zic1 zic1.L zic1.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.52533 [+] Xl.1796
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 64 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine zic1 zic1.L zic1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ZIC1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Zic1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR zic1 ZFIN Ensembl
chicken
GEISHA ZIC1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Uptake of 3H-glycine in the outer plexiform layer of the retina of the toad, Bufo marinus. [J Comp Neurol 1984]
Most recent: The b-HLH transcription factor Hes3 participates in neural plate border formation by interfering with Wnt/β-catenin signaling. [Dev Biol 2018]
View All Papers 30 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 0 term 17 terms
PANTHER zic1
KEGG Pathways K09224
KOG [R] FOG: Zn-finger
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino zic1 MO1 zic1 MO1 zic1 MO1
Affymetrix 1.0 Str.17224.1.S1_at [+] Xl.1796.1.S1_at [+]
Affymetrix 2.0 Xl2.1796.1.S2_at [+]

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556