Gene Symbol: sia2 [provisional] Gene Name: siamois homeodomain 2 [provisional] Synonyms: xtwn, twin Add Xenopus synonyms Gene Function: homeodomain transcription factor Interactants: sia1(10) , gsc(7) , lef1(5) , tcf3(5) , nodal(4) , tgfb1(4) , chrd(3) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002942160|PREDICTED: Xenopus (Silurana) tropicalis homeobox protein siamois-like (LOC100489935), mRNA ATGACTTGTGACTCTGAGCTTGAGCAGATCATCTACACAGCACTGACCCTACAAGATGACTATCCACCACCACCGAGGGACCAAGACAAATCCAGCTCCAGCCTTTTTGGCCTGATTCCTGATCCTCTCCCAGGGGTGGAAAACCAGGGAATCCTGCAGAAGACTATATGGGAACTTTATTCTGTCCTTGGGATCCCACAGGATTCTTTTTTAAACAGAAGCTTGAAGCATCATGATCTAGAACCCAACAAGGAGTCACTATCCACTAACAATGAGATATCCAAGGGCCGTAAACGGCCATTGTATGAAGAGGAGCAGAGGGAAAGCAAGAAGCCCAAATTAGAGATGGATCACTACCTGCCATCTGCTCGCACCAGGTGTAGGAGAAGAACCATTTATTCCAAGGAACAGACCATCTTCCTGCAGGATCAATTTGATCTCAACCCCTATCCGGACTTTGTGAGCAGATGCCACATTGCCAAGATAACTGGGATCCCAGAGCCCAGGATACAGGTTTGGTTCCAGAACAGAAGAGCCAGGCATCTGCTCAGAGCCACCGGTTCTCAGGTTCCCCATGGAAATACATCACTGACTGAAGAAGAACCCAGATGCTTCATCTACGGAGAAACTCAATATCCGGATATGTGGGGCTAA	Refseq >NM_001085676|Xenopus laevis siamois homeodomain 2 (sia2), mRNA GCAGCACAGACATGACTTGTGACTCTGAACTTGAGCAAATCATCTACACAGCGCTGACCCTACAAGATGACTATCCTGTGTTCTGCCCACCACAGAGGGACCAAACCAAATCCTGCTCCAGCTCTTTTGGTATGTTTCCTGATTCTTATCCAGGGGTGGGAAACCAGGGAATCTTGCAGGAGACTATAAGAGAACTTTATTCTGTCCTTGGGATCCCACAAGATTCTCATTTTAACAGAAGCATGAAGCATCATCTCCTAGAACCCAAGAAGGCGACACTATCTACTGGGATCTACGCCAAACCAACCTGCAATCAGACACCTAAAGCCTGTAAACGGCCATTTTGTGAAGAGGAGCAGAGGGAAGGTAAAAAGCCCAGAATAGAGATGGATCATTTCCTACCATCGGCACCCAACAGGTGTAGGAGAAGAACCATTTATTCAAAGGAGCAAATCCTCTTCCTCCAGAATCAATTTGATCTCAATCCCTATCCAGACTTTGTGAAGAGATGCCACATTGCAAAGATAACTGGGATCCCAGAGCCCAGGATTCAGGTTTGGTTCCAGAACAGAAGAGCCAGGCATCTGCTCAGAGCCATCAATCTCAGGTTCCCCAAGAAAAGAGATCAGCAGCTGCAGAAGAACCCAGATGCTTTACCTACGAGAACCCCAGTATCCAGACATGTGGGGCTAAGCAAAATACTCCCTTACACGTAGCATGTACCCAAAGTCATGACTGAATCACTGCAGTGACATTTGTACCTTGAGACACCTATATGCAAAGAATTCAAATTACTTTTTTTTTGGCTGAAATATTTGTCACTATGTACATAGAGAAATTAACTACTACTTTAAATTTGACGTCCCTTAATGTATAACGTAAATATTTTAAATATTAGAATTAAAGGTATGGGATAGGTTCATATACTCTATTATTACTCTTTATTTAAACAAGTTTCATTTACTGAAAGTGTATCGCTTTAGTCCATAAAAAAACATGTTTATATGATATAAAGTCAGTATTTAAATTTATCAATAATTTATTCATTATTGTTCCCATGGGACCTTATATAAATATAATTGCTTTATCAGCACTTCTCACTGTATTGTGTTATAAGGAGTACAGTTTAAGATACGCATGGCAACACACAGTACTTGATTTCAGAAGTCAATTTGTTTTATCTTAAGACAATAGTTGGCATTTAATGGTATAAATATATGTATTTTAATTTTTGTGATATTGCTTGGTAATCAATAAAATTGTATCTTTTTTT
Protein		NCBI Protein >XP_002942206|PREDICTED: homeobox protein siamois-like [Xenopus (Silurana) tropicalis] MTCDSELEQIIYTALTLQDDYPPPPRDQDKSSSSLFGLIPDPLPGVENQGILQKTIWELYSVLGIPQDSFLNRSLKHHDLEPNKESLSTNNEISKGRKRPLYEEEQRESKKPKLEMDHYLPSARTRCRRRTIYSKEQTIFLQDQFDLNPYPDFVSRCHIAKITGIPEPRIQVWFQNRRARHLLRATGSQVPHGNTSLTEEEPRCFIYGETQYPDMWG	Refseq >NP_001079145|siamois homeodomain 2 [Xenopus laevis] MTCDSELEQIIYTALTLQDDYPVFCPPQRDQTKSCSSSFGMFPDSYPGVGNQGILQETIRELYSVLGIPQDSHFNRSMKHHLLEPKKATLSTGIYAKPTCNQTPKACKRPFCEEEQREGKKPRIEMDHFLPSAPNRCRRRTIYSKEQILFLQNQFDLNPYPDFVKRCHIAKITGIPEPRIQVWFQNRRARHLLRAINLRFPKKRDQQLQKNPDALPTRTPVSRHVGLSKILPYT

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene			Xl.390
Unigene EST Profile			EST Profile
GEO data			GEO
Images		2 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human
mouse
zebrafish

Publications
First:		Pattern formation in 8-cell composite embryos of Xenopus laevis. [J Embryol Exp Morphol 1986]
Most recent:		Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos. [Proc Natl Acad Sci U S A 2012]
		View All Papers 6 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[R] Transcription factor, contains HOX domain

Reagents		tropicalis	laevis
Clones			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0		StrJgi.6297.1.S1_at	Xl.390.1.S1_at
Affymetrix 2.0			Xl2.390.1.S1_at

Symbol legend[+]

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