Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (11) GO Terms (6) Nucleotides (1034) Proteins (26) Interactants (282) Wiki
XB-GENEPAGE- 482184

Gene Symbol: tubb

Gene Name: tubulin beta class I

Synonyms: XLOT , tubulin beta-1 , tubb beta-5 , beta5-tubulin , tubb5
Add Xenopus synonyms , Nomenclature history


Gene Function: microtubule component

Protein Function :
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


Interactants: Loading ...

Disease Ontology Associations: COMPLEX CORTICAL DYSPLASIA WITH OTHER BRAIN MALFORMATIONS 6

OMIM Disease Associations: TUBULIN, BETA; TUBB [+]
 
Xenbase Gene ID XB-GENE-482185 XB-GENE-864839 XB-GENE-17336360
Gene Symbol tubb tubb.L tubb.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.65406 [+] Xl.46552 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 18 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tubb tubb.L tubb.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TUBB OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
Gm9007 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
GEISHA TUBB Ensembl
fruit fly
worm
WORMBASE
Publications
First: Specific inhibition of beta-tubulin synthesis in Xenopus oocytes using anti-sense oligodeoxyribonucleotides. [Gene 1988]
Most recent: Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation. [Development 2017]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 6 terms 0 term
PANTHER tubb
KEGG Pathways K07375 K07375
KOG [Z] Beta tubulin
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Tubb Ab1 , Tubb Ab2 Tubb Ab1 , Tubb Ab2
ORF tubb ORF1
Affymetrix 1.0 Str.6667.1.S1_at [+] Xl.8589.1.S1_at [+]
Affymetrix 2.0 Xl2.46552.2.S1_at [+]

Symbol legend[+]
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.9.0
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556