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Summary Expression Gene Literature (266) GO Terms (11) Nucleotides (4) Proteins (0) Interactants (882) Wiki
Gene Symbol: sia1

Gene Name: siamois homeodomain 1

Synonyms: Xsia , Siamois , sia ( Add synonyms , Nomenclature history )

Gene Function: homeodomain transcription factor

Protein Function :
Essential for Wnt/beta-catenin-mediated formation of the Spemann organizer and for induction of the organizer precursor, the Nieuwkoop center. Acts as a transcriptional activator, cooperating with TGFb...[+]

Interactants: Loading ...
Diseases:  External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER

GEO Series : GSE93195.
Xenbase Gene ID XB-GENE-482368 XB-GENE-864865 XB-GENE-17331825
Gene Symbol sia1 sia1.L sia1.S
Chromosome scaffold_48 chr3L Scaffold20
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100038038
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot TrEMBL TrEMBL RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine sia1 sia1.L sia1.S
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM Protein Atlas, Allen Brain Atlas
MGI, IMPC Eurexpress, MGI, Allen Brain Atlas
fruit fly
First Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis., Cell 1995                
Most Recent PTK7 proteolytic fragment proteins function during early Xenopus development., Dev Biol 2019          
All View All Papers 52 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 10 terms 0 term
KEGG Pathways
KOG [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks sia1
Morpholinos sia1 MO1 , sia1 MO2 sia1 MO1 , sia1 MO2 sia1 MO1 , sia1 MO2
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.13.0

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