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Summary Expression Gene Literature (19) GO Terms (6) Nucleotides (41) Proteins (17) Interactants (259) Wiki
XB-GENEPAGE- 482418

Gene Symbol: hnf4a

Gene Name: hepatocyte nuclear factor 4 alpha

Synonyms: HNF-4-alpha , hnf4 , nr2a1
Add Xenopus synonyms , Nomenclature history


Gene Function: steroid hormone receptor, transcription factor

Protein Function:
Transcription factor; binds and activates the promoter for the HNF1-alpha gene. Potential initiator of a transcriptional cascade within a subset of cells committed to a specific developmental program. ...[+]


Interactants: Loading ...

OMIM Disease Associations: DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]
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Xenbase Gene ID XB-GENE-482419 XB-GENE-17337466 XB-GENE-864872
Gene Symbol hnf4a hnf4a.L hnf4a.S
Chromosome Chr10 Scaffold14557
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Xl.1217
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 22 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine hnf4a hnf4a.L hnf4a.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HNF4A OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Hnf4a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN hnf4a ZFIN Ensembl
chicken
GEISHA HNF4A Ensembl
fruit fly
worm
WORMBASE
Publications
First: Elements and factors involved in tissue-specific and embryonic expression of the liver transcription factor LFB1 in Xenopus laevis. [Mol Cell Biol 1993]
Most recent: Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors. [Nat Cell Biol 2016]
View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 6 terms
EC
PANTHER hnf4a
KEGG Pathways K07292
KOG [K] Hepatocyte nuclear factor 4 and similar steroid hormone receptors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
ORF hnf4a ORF1
Affymetrix 1.0 Str.36814.2.S1_at [+] Xl.1217.1.S1_at [+]
Affymetrix 2.0 Xl2.1217.1.S1_at [+]

Symbol legend[+]

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