Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (68) GO Terms (9) Nucleotides (126) Proteins (32) Interactants (1140) Wiki
XB-GENEPAGE- 483192

Gene Symbol: hesx1

Gene Name: HESX homeobox 1

Synonyms: rpx , Xanf1 , Xanf-1 , Xanf , XANF-2 , Xanf2 , anf2 , hesx1-b , hesx1-a
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:
Regulates the earliest stages of development of the anterior neural plate. Plays a role in forebrain development by inhibiting the expression of otx2 and pax6 in the rostral region of the anterior neur...[+]


Interactants: Loading ...

OMIM Disease Associations: SEPTOOPTIC DYSPLASIA
1/2
 
Xenbase Gene ID XB-GENE-483193 XB-GENE-864952 XB-GENE-6252654
Gene Symbol hesx1 hesx1.L hesx1.S
Chromosome scaffold_4 Scaffold33876 Scaffold177844
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.27088 Xl.131 Xl.1003
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 38 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine hesx1 hesx1.L hesx1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu069m07      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HESX1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Hesx1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN hesx1 ZFIN Ensembl
chicken
GEISHA HESX1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: A novel homeobox gene expressed in the anterior neural plate of the Xenopus embryo. [Dev Biol 1992]
Most recent: HMG-box factor SoxD/Sox15 and homeodomain-containing factor Xanf1/Hesx1 directly interact and regulate the expression of Xanf1/Hesx1 during early forebrain development in Xenopus laevis. [Gene 2018]
View All Papers 18 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 7 terms 4 terms
EC
PANTHER hesx1
KEGG Pathways K09354 K09354 K09354
KOG [R] Transcription factor, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino hesx1 MO1 , hesx1 MO2 , hesx1 MO3 , hesx1 MO4 hesx1 MO1 , hesx1 MO2 , hesx1 MO3 , hesx1 MO4 hesx1 MO1 , hesx1 MO2 , hesx1 MO3 , hesx1 MO4
Affymetrix 1.0 Str.27088.1.S1_at Xl.131.1.S1_at Xl.1003.1.S1_at
Affymetrix 2.0 Xl2.131.1.A1_at Xl2.1003.1.A1_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.6.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556