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Summary Expression Gene Literature (329) GO Terms (16) Nucleotides (192) Proteins (22) Interactants (1229) Wiki
XB-GENEPAGE- 479317

Gene Symbol: notch1

Gene Name: notch 1

Synonyms: notch , xotch , xnotch , notch-1 , xnotch1 , x-notch-1
Add Xenopus synonyms , Nomenclature history


Gene Function: signal transduction, receptor for delta class ligands

Protein Function:
Functions as a receptor for membrane-bound ligands jagged1, jagged2 and delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it form...[+]


Interactants: Loading ...

OMIM Disease Associations: AORTIC VALVE DISEASE 1; AOVD1
1/5
 
Xenbase Gene ID XB-GENE-479318 XB-GENE-17342057 XB-GENE-865261
Gene Symbol notch1 notch1.L notch1.S
Chromosome Chr02 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.59603 [+] Xl.1057 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 68 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine notch1 notch1.L notch1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NOTCH1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Notch1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN notch1a notch1b ZFIN Ensembl
chicken
GEISHA NOTCH1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Cell patterning in pigment-chimeric eyes in Xenopus: germinal transplants and their contributions to growth of the pigmented retinal epithelium. [Proc Natl Acad Sci U S A 1987]
Most recent: Evo-engineering and the cellular and molecular origins of the vertebrate spinal cord. [Dev Biol 2017]
View All Papers 53 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 12 terms 8 terms 12 terms
EC
PANTHER notch1
KEGG Pathways K02599 K02599 K02599
KOG [O] 26S proteasome regulatory complex, subunit PSMD10
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 4 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino notch1 MO1 notch1 MO1 notch1 MO1
Affymetrix 1.0 Str.51150.1.S1_at [+] Xl.1057.1.S1_at
Affymetrix 2.0 Xl2.1057.1.S1_at

Symbol legend[+]

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