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Summary Expression Gene Literature (334) GO Terms (17) Nucleotides (195) Proteins (25) Interactants (1287) Wiki
XB-GENEPAGE-479317

Gene Symbol: notch1

Gene Name: notch 1

Synonyms: notch , xotch , xnotch , notch-1 , xnotch1 , x-notch-1 ( Add Xenopus synonyms , Nomenclature history )

Gene Function: signal transduction, receptor for delta class ligands

Protein Function :
Functions as a receptor for membrane-bound ligands jagged1, jagged2 and delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it form...[+]

Interactants: Loading ...
Disease Ontology: AORTIC VALVE STENOSIS

OMIM Diseases: AORTIC VALVE DISEASE 1; AOVD1 [+]
1/5
 
Xenbase Gene ID XB-GENE-479318 XB-GENE-17342057 XB-GENE-865261
Gene Symbol notch1 notch1.L notch1.S
Chromosome Chr02 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq NCBI Nucleotide Refseq
Protein Refseq Swiss-Prot TrEMBL Swiss-Prot NCBI Protein TrEMBL Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images                   Ensembl In situ: Single cell: RNA-Seq:  
Data Mining tropicalis laevis.L laevis.S
XenMine notch1 notch1.L notch1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NOTCH1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Notch1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR notch1a notch1b ZFIN Ensembl
chicken
GEISHA NOTCH1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Cell patterning in pigment-chimeric eyes in Xenopus: germinal transplants and their contributions to growth of the pigmented retinal epithelium., Proc Natl Acad Sci U S A 1987            
Most recent Bisphenol F Disrupts Thyroid Hormone Signaling and Postembryonic Development in Xenopus laevis., Environ Sci Technol 2018  
All View All Papers 53 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 9 terms 13 terms
PANTHER notch1
KEGG Pathways K02599 K02599 K02599
KOG [O] 26S proteasome regulatory complex, subunit PSMD10
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 4 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Morpholino notch1 MO1 notch1 MO1 notch1 MO1
Affymetrix 1.0 Str.51150.1.S1_at [+] Xl.1057.1.S1_at
Affymetrix 2.0 Xl2.1057.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.10.0


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