actc1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (62)

Nucleotides (2455)

Interactants (184)

XB-GENEPAGE-480346

Gene Symbol: actc1 Gene Name: actin, alpha, cardiac muscle 1 Synonyms: cardiac actin, actc Add Xenopus synonyms Gene Function: cytoskeletal constituent Interactants: myod1(20) , myf5(10) , nkx2-5(9) , act3(7) , gsc(7) , srf(7) , t(7) View All

XB-GENE-480347

XB-GENE-865367

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_203763\|Xenopus (Silurana) tropicalis actin, alpha, cardiac muscle 1 (actc1), mRNA TTAATCACAGCAACCAGCTCTCCTGTGCTGACCAGAACCTAACCTGCCACTATGTGTGACGACGAGGAGACTACCGCCTTGGTGTGCGACAATGGCTCCGGGCTGGTGAAGGCTGGGTTCGCTGGGGATGATGCCCCACGTGCTGTGTTCCCCTCCATCGTTGGTCGCCCCCGTCACCAGGGTGTCATGGTGGGTATGGGTCAGAAAGACTCCTACGTAGGTGATGAAGCTCAGAGCAAGAGAGGTATCCTGACCCTGAAGTACCCCATTGAACACGGTATCATCACCAACTGGGATGATATGGAGAAGATCTGGCACCACACCTTCTACAATGAGCTGCGTGTGGCCCCTGAGGAGCACCCCACCCTGCTCACTGAGGCCCCACTGAACCCCAAGGCCAACCGTGAAAAGATGACACAGATCATGTTTGAGACCTTCAACGTCCCAGCCATGTATGTTGCCATCCAGGCTGTGCTGTCCCTGTACGCTTCTGGTCGTACCACAGGTATCGTTCTTGACTCCGGTGATGGTGTCACCCACAATGTCCCCATCTATGAAGGTTATGCCCTGCCCCATGCCATCATGCGTCTGGACCTGGCTGGTAGAGACCTCACAGATTACCTCATGAAAATCCTGACTGAACGTGGCTACTCTTTTGTCACCACAGCTGAACGTGAAATTGTCCGTGACATCAAGGAAAAGCTGTGCTATGTGGCTTTGGACTTTGAGAATGAAATGGCCACCGCTGCCTCTTCCTCCTCCCTGGAGAAGAGCTATGAGCTTCCCGACGGTCAGGTCATCACCATTGGAAATGAACGTTTCCGCTGCCCTGAGACCCTCTTCCAGCCTTCCTTCATTGGTATGGAATCTGCTGGTATCCATGAAACTACCTACAACAGCATCATGAAATGCGACATTGATATCCGCAAGGACCTGTACGCCAACAATGTCCTCTCTGGTGGTACCACCATGTACCCTGGTATTGCTGACAGAATGCAGAAGGAAATCACTGCCTTGGCTCCCAGCACCATGAAGATCAAGATCATTGCCCCACCTGAGCGTAAATACTCAGTCTGGATCGGTGGCTCCATCTTGGCCTCCCTGTCCACCTTCCAACAGATGTGGATCAGCAAACAGGAATACGATGAGGCAGGCCCCTCCATTGTGCACAGGAAGTGCTTCTAAACATTACGCACACTCCTCCAAGCAACACATACAAAGTACCTCAAAGTCGAAGAAAACAAGACCTGGACAGTCACTGTACAGTTTGTTTACACTCCATCATATTTATTACTTTCTAAATAAAACACAAGCGGTTACGTTAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001086591\|Xenopus laevis actin, alpha, cardiac muscle 1 (actc1), mRNA CCAGAACATAACCTGCCACTATGTGTGACGACGAGGAGACTACCGCCTTGGTGTGCGACAATGGCTCCGGGCTGGTGAAGGCTGGGTTCGCTGGGGATGATGCCCCCCGTGCTGTGTTCCCCTCCATCGTTGGTCGCCCCCGTCATCAGGGTGTCATGGTGGGTATGGGTCAGAAAGACTCCTACGTAGGTGATGAAGCTCAGAGCAAGAGAGGTATCCTGACCCTGAAGTACCCCATTGAGCACGGTATCATCACTAACTGGGATGATATGGAGAAGATCTGGCACCACACCTTCTACAATGAGCTGCGTGTGGCCCCTGAAGAGCACCCCACCCTGCTCACTGAGGCCCCACTGAACCCCAAGGCCAACCGTGAAAAGATGACACAGATCATGTTTGAGACCTTCAACGTCCCAGCCATGTATGTTGCCATCCAGGCTGTGCTGTCCCTGTACGCTTCTGGTCGTACCACAGGTATCGTTCTTGACTCTGGTGATGGTGTCACCCACAATGTCCCCATCTATGAAGGTTATGCTCTGCCCCATGCCATCCAGCGTCTGGACCTGGCTGGTAGAGACCTCACAGATTACCTCATGAAGATCCTGACTGAACGTGGCTACTCCTTTGTGACAACAGCTGAACGGGAAATTGTCCGTGACATCAAGGAAAAGCTGTGCTATGTGGCTTTGGACTTTGAGAATGAAATGGCCACCGCTGCCTCATCCTCCTCCCTGGAGAAGAGCTATGAGCTTCCCGACGGTCAGGTCATCACCATTGGAAATGAACGTTTCCGTTGCCCTGAGACCCTCTTCCAGCCTTCCTTCATTGGTATGGAATCTGCCGGTATCCATGAAACTACCTACAACAGCATCATGAAATGCGACATTGATATCCGCAAGGACCTGTACGCCAACAACGTCCTCTCTGGTGGTACCACCATGTACCCTGGTATTGCTGACAGAATGCAGAAGGAGATCACTGCCCTGGCCCCCAGCACCATGAAGATCAAGATCATTGCCCCACCTGAGCGTAAATACTCCGTCTGGATCGGTGGCTCCATCTTGGCCTCTCTGTCCACCTTCCAACAGATGTGGATCAGCAAACAGGAATACGATGAGGCAGGACCCTCCATTGTGCACAGGAAGTGCTTCTAAACATTACACACACTCCTCCAAGCAACATATACAGAGTACCTCAAAGTCAAAGAAAACAAGACCTGGACAGTCACTGTACAGTTTGTTTACACGCCATCATATTTATTACTTTCTAAATAAAACACATGCGGTTAAGTTCATCAGAGTGTGACTGTCTTCTTTTGGATGTTATGCTTTGCCAATAAAAGGAAACATCGGCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_989094\|actin, alpha, cardiac muscle 1 [Xenopus (Silurana) tropicalis] MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF UniProtKB	Refseq >NP_001080060\|actin, alpha cardiac muscle 1 [Xenopus laevis] MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIQRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.66747 [+] Str.33599 Str.11672 Str.38453 Str.66811 Str.66844 Str.84707	Xl.1115 [+] Xl.59598 Xl.55416 Xl.76245 Xl.80580 Xl.80733 Xl.81236 Xl.83266 Xl.83841
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		39 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	ACTC1	OMIM:192600 OMIM:612098
mouse		MGI	Actc1	All(5) Targeted, knock Out(2) Targeted, other(3)
zebrafish		ZFIN	acta1b	2 Lines(s)

Publications
First:		Cell type-specific activation of actin genes in the early amphibian embryo. [Nature 1984]
Most recent:		Tcf21 regulates the specification and maturation of proepicardial cells. [Development 2013]
		View All Papers 8 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		motor activity protein binding structural constituent of cytoskeleton
Biological:
Cellular Component:		actin filament
EC:
KOG:		[Z] Actin and related proteins

Reagents		tropicalis	laevis
Clones			EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.6713.1.S1_at [+] Str.33599.1.A1_at Str.38453.1.S1_at Str.38916.1.A1_at Str.43910.1.A1_at
Affymetrix 2.0			Xl2.1115.1.S1_at [+] Xl2.55416.1.A1_x_at Xl2.55416.1.A1_at Xl2.55416.1.A1_s_at

Symbol legend[+]