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Summary Expression Gene Literature (86) GO Terms (16) Nucleotides (80) Proteins (28) Interactants (378) Wiki
XB-GENEPAGE- 484756

Gene Symbol: nr3c1

Gene Name: nuclear receptor subfamily 3 group C member 1

Synonyms: xGR , gcr , gccr , grl , glucocorticoid receptor , nr3c1-a , nr3c1-b
Add Xenopus synonyms , Nomenclature history


Gene Function: steroid hormone receptor

Protein Function:
Receptor for glucocorticoids (GC) (PubMed:8018720). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, an...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-484757 XB-GENE-865499 XB-GENE-6252633
Gene Symbol nr3c1 nr3c1.L nr3c1.S
Chromosome scaffold_3 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq NCBI Nucleotide
Protein Refseq TrEMBL Refseq TrEMBL Swiss-Prot NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.19460 Xl.1201 Xl.57154
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 3 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine nr3c1 nr3c1.L nr3c1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NR3C1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Nr3c1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN nr3c1 ZFIN Ensembl
chicken
GEISHA NR3C1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Mitotic activity of germ cells during normal development of Xenopus laevis tadpoles. [J Embryol Exp Morphol 1975]
Most recent: Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors. [Nat Cell Biol 2016]
View All Papers 9 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 16 terms 7 terms
EC
PANTHER nr3c1
KEGG Pathways K05771 K05771 K05771
KOG [K] Hepatocyte nuclear factor 4 and similar steroid hormone receptors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Nr3c1 Ab1
ORF nr3c1 ORF1
Affymetrix 1.0 Str.19460.1.A1_at Xl.1201.1.S1_at Xl.21632.1.S1_s_at [+]
Affymetrix 2.0 Xl2.1201.1.S1_at [+] Xl2.21632.1.S1_at

Symbol legend[+]

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