Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (4) GO Terms (3) Nucleotides (111) Proteins (21) Interactants (129) Wiki
Gene Symbol: ptpn6

Gene Name: protein tyrosine phosphatase non-receptor type 6

Synonyms: SHP1 , SHP-1 ( Add synonyms , Nomenclature history )

Gene Function: intracellular signaling

Protein Function :

Interactants: Loading ...
Diseases:  External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
Xenbase Gene ID XB-GENE-487863 XB-GENE-865744 XB-GENE-17344969
Gene Symbol ptpn6 ptpn6.L ptpn6.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100144699
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq TrEMBL RefSeq TrEMBL NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ptpn6 ptpn6.L ptpn6.S
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards PTPN6 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Ptpn6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR ptpn6 ZFIN Ensembl
fruit fly
First Structural determinants of SHP-2 function and specificity in Xenopus mesoderm induction., Mol Cell Biol 1998  
Most Recent JAK-STAT pathway activation in response to spinal cord injury in regenerative and non-regenerative stages of Xenopus laevis., Regeneration (Oxf) 2017                            
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 2 terms 1 terms
KEGG Pathways K05697 K05697 K05697
KOG [T] Protein tyrosine phosphatase Corkscrew and related SH2 domain enzymes
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ptpn6
ORFs ptpn6.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.13.0

Major funding for Xenbase is provided by grant P41 HD064556