acta2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (4)

Nucleotides (659)

Interactants (33)

XB-GENEPAGE-493936

Gene Symbol: acta2 Gene Name: actin, alpha 2, smooth muscle, aorta Synonyms: aat6, actsa, mymy5, alpha smooth muscle actin, a-sma, sm-actin, SMactin, alpha-SM-actin, ASMA Add Xenopus synonyms Gene Function: cytoskeletal constituent Interactants: fgf4(2) , gata2(2) , Acta2 Ab1(1) , act3(1) , amh(1) , ash2l(1) , bmp4(1) View All

XB-GENE-493937

XB-GENE-866302

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001011250\|Xenopus (Silurana) tropicalis actin, alpha 2, smooth muscle, aorta (acta2), mRNA CCGAGAGGGTTTCTTGTTGGAAAGGTTTAAGCAAGTAGCAATACAAGATGTGCGACGAGGAAGACACTACTGCACTGGTGTGCGACAACGGCTCTGGGCTCTGCAAGGCTGGGTTTGCTGGGGACGATGCTCCAAGGGCCGTATTCCCTTCCATCGTGGGTCGCCCCAGGCACCAGGGTGTGATGGTTGGTATGGGTCAGAAGGACAGCTATGTTGGTGATGAAGCTCAGAGCAAGAGAGGTATCCTGACACTGAAGTACCCAATTGAACATGGCATCATTACAAACTGGGATGATATGGAGAAGATCTGGCACCACAGCTTCTACAATGAATTACGAGTGGCCCCCGAGGAACACCCAACCCTGCTCACTGAGGCTCCACTGAATCCCAAAGCAAACAGAGAAAAAATGACCCAGATAATGTTCGAGACATTTAACGTCCCCGCAATGTACGTTGCTATTCAGGCAGTGCTATCCCTCTATGCCTCTGGCCGTACTACTGGTATCGTACTTGACTCTGGTGATGGTGTCACCCACAACGTACCAATCTATGAAGGGTATGCTCTCCCTCATGCAATCATGCGTCTTGACCTGGCTGGCCGTGACCTAACAGACTACCTCATGAAGATCTTGACTGAACGCGGCTATTCCTTCGTAACTACTGCTGAGCGTGAAATCGTGCGAGACATCAAGGAGAAGCTGTGCTACGTAGCCCTCGACTTTGAGAATGAAATGGCGACCGCCGCCTCTTCCTCCTCTCTGGAAAAGAGCTACGAACTTCCCGACGGTCAGGTCATCACAATTGGAAATGAGCGTTTCCGCTGCCCCGAGACCCTGTTCCAGCCATCCTTCATTGGTATGGAATCTGCTGGCATCCATGAAACCACATACAACAGCATCATGAAATGCGACATAGACATCAGGAAGGACCTGTATGCCAACAACGTACTGTCCGGTGGCACCACCATGTACCCCGGCATCGCTGACAGAATGCAGAAGGAGATCACAGCTTTGGCCCCCAGCACAATGAAAATCAAGATCATTGCCCCACCTGAGCGCAAGTACTCCGTCTGGATTGGTGGATCCATCCTCGCCTCCCTGTCTACCTTCCAGCAGATGTGGATCAGCAAACCCGAATACGACGAAGCCGGCCCCTCCATTGTTCACCGCAAATGCTTCTAAAAAAAAAAAAAAAAAAAAAAAAAGG	Refseq >NM_001091337\|Xenopus laevis actin, alpha 2, smooth muscle, aorta (acta2), mRNA CCCACGCGTCCGAGCAACCCCAGCAAAGCACCGAGAGGGTTTCTTGTTGGAAAGGCTTTAGCAAGTAGCAATACAAGATGTGTGACGAAGAAGACACTACTGCACTGGTGTGTGACAATGGCTCTGGACTCTGCAAGGCTGGATTTGCTGGGGACGATGCTCCAAGGGCCGTATTCCCCTCCATCGTGGGTCGCCCCAGGCACCAGGGTGTGATGGTTGGTATGGGTCAGAAGGACAGCTATGTTGGTGATGAAGCTCAGAGCAAGAGAGGTATTCTGACACTGAAATACCCAATTGAACACGGCATCATTACAAACTGGGATGACATGGAGAAGATCTGGCACCACAGCTTCTACAATGAATTACGAGTGGCCCCAGAGGAACACCCAACCCTGCTCACTGAGGCTCCACTGAATCCCAAAGCTAACAGAGAAAAAATGACCCAGATAATGTTTGAGACATTTAACGTGCCAGCAATGTACGTTGCTATTCAGGCGGTGCTATCCCTCTATGCTTCTGGCCGTACTACTGGTATCGTACTTGACTCTGGTGATGGTGTCACCCACAATGTACCAATCTATGAAGGGTATGCTCTTCCTCATGCAATCATGCGTCTTGACCTGGCTGGCCGTGACCTAACAGACTACCTCATGAAGATCTTGACTGAACGCGGCTATTCCTTTGTAACTACTGCTGAGCGTGAAATTGTGCGAGACATCAAGGAGAAGCTGTGCTATGTAGCCCTTGACTTTGAGAATGAAATGGCTACCGCTGCCTCTTCCTCCTCTCTGGAAAAGAGTTATGAACTTCCCGACGGTCAGGTCATCACAATTGGAAATGAGCGTTTCCGCTGCCCCGAGACCCTGTTCCAGCCATCTTTCATTGGTATGGAATCTGCCGGTATCCATGAAACCACTTACAACAGCATCATGAAATGCGACATAGACATCCGAAAGGACCTGTATGCCAACAACGTACTGTCCGGTGGTACCACCATGTACCCTGGCATTGCTGACAGAATGCAGAAGGAGATCACTGCTTTGGCCCCCAGCACAATGAAAATCAAGATCATTGCCCCACCTGAGCGTAAGTACTCCGTCTGGATTGGTGGCTCCATCCTCGCCTCCCTGTCTACCTTCCAGCAGATGTGGATCAGCAAACCCGAATACGACGAAGCCGGCCCCTCCATTGTTCACCGCAAATGCTTCTAAAAAATGTCCTTTTCTTTATTTTATTATTTTTTATTCCAGCCTATAACTGTGAGTGTGCTCCAAAAAATGAAGAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001011250\|actin, alpha 2, smooth muscle, aorta [Xenopus (Silurana) tropicalis] MCDEEDTTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF	Refseq >NP_001084806\|actin, alpha 2, smooth muscle, aorta [Xenopus laevis] MCDEEDTTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.67011 [+] Str.67294	[+] Xl.76413 Xl.57275
Unigene EST Profile		EST Profile
GEO data			GEO
Images		8 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	ACTA2	OMIM:611788
mouse		MGI	Acta2	All(4) Targeted, knock Out(2) Targeted, other(2)
zebrafish		ZFIN	acta2

Publications
First:		Ventrolateral regionalization of Xenopus laevis mesoderm is characterized by the expression of alpha-smooth muscle actin. [Development 1992]
Most recent:		WD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2. [J Biol Chem 2011]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		motor activity protein binding structural constituent of cytoskeleton
Biological:
Cellular Component:		actin filament
EC:
KOG:		[Z] Actin and related proteins

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Str.5014.1.S1_at	Xl.25861.1.S1_at
Affymetrix 2.0			Xl2.25861.1.S1_at

Symbol legend[+]