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Summary Expression Gene Literature (154) GO Terms (20) Nucleotides (39) Proteins (20) Interactants (580) Wiki
XB-GENEPAGE-866804
Gene Symbol:
slc12a3

Gene Name:
solute carrier family 12 member 3

Synonyms:
ncct , tsc , ncc ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane solute exchange

Protein Function :
Reversible hydration of carbon dioxide.


InterPro :
Carbonic anhydrase CA14 , CA dom sf , CA dom , Carbonic anhydrase a-class CS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Gitelman syndrome

OMIM:
GITELMAN SYNDROME; GTLMNS

External Links:
1/2
 
Xenbase Gene ID XB-GENE-866805 XB-GENE-6488610 XB-GENE-17345760
Gene Symbol slc12a3 slc12a3.L slc12a3.S
Chromosome Chr4 Scaffold109694
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 6.0
CDS Gene model
Entrez Gene 100494755
mRNA NCBI Nucleotide
Protein NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine slc12a3 slc12a3.L slc12a3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards SLC12A3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Slc12a3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Slc12a3 Ensembl
zebrafish
ZFIN, AGR slc12a3 ZFIN Ensembl
chicken
GEISHA SLC12A3 Ensembl
fruit fly
Publications
First Thiosemicarbazide-induced osteolathyrism in metamorphosing Xenopus laevis., J Exp Zool 1983  
Most Recent A novel homozygous mutation (p.N958K) of SLC12A3 in Gitelman syndrome is associated with endoplasmic reticulum stress., J Endocrinol Invest 2021  
All View All Papers 17 paper(s) referencing morpholinos 12 paper(s) referencing OMIMs 18 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 20 terms 0 term 0 term
PANTHER slc12a3
KEGG Pathways
KOG [P] Na+/K+ symporter
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks slc12a3
Clones Horizon Source BioScience
Plasmids Addgene Addgene

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