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Summary Expression Gene Literature (22) GO Terms (6) Nucleotides (322) Proteins (46) Interactants (1049) Wiki
XB-GENEPAGE-868116
Gene Symbol:
tle5

Gene Name:
TLE family member 5, transcriptional modulator

Synonyms:
xgrg-5 , grg , esp1 , grg5 , aes-1 , aes-2 , aes ( Add synonyms , Nomenclature history )

Gene Function:
transducin-like enhancer of split

Protein Function :
May act as a transcriptional corepressor. Has a possible role in the negative regulation of proteins containing WD-40 repeats. May be required for the initiation and maintenance of the differentiated s...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-868117 XB-GENE-17342204 XB-GENE-868124
Gene Symbol tle5 tle5.L tle5.S
Chromosome Chr01 chr1L Scaffold21
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 733921
379357
398976
mRNA RefSeq RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tle5 tle5.L tle5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TLE5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tle5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tle5 Ensembl
zebrafish
ZFIN, AGR tle5 ZFIN Ensembl
chicken
GEISHA AES Ensembl
fruit fly
worm
Publications
First Cloning and developmental expression of Xenopus cDNAs encoding the Enhancer of split groucho and related proteins., Gene 1997  
Most Recent A single KH domain in Bicaudal-C links mRNA binding and translational repression functions to maternal development., Development 2019                  
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 6 terms 2 terms 2 terms
PANTHER tle5
KEGG Pathways
KOG [B] Transducin-like enhancer of split protein (contains WD40 repeats)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tle5
ORFs aes ORF1 aes.L ORF1 aes.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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