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Summary Expression Gene Literature (22) GO Terms (6) Nucleotides (300) Proteins (38) Interactants (972) Wiki
XB-GENEPAGE-868116
Gene Symbol: tle5

Gene Name: TLE family member 5, transcriptional modulator

Synonyms: xgrg-5 , grg , esp1 , grg5 , aes-1 , aes-2 , aes ( Add synonyms , Nomenclature history )

Gene Function: transducin-like enhancer of split

Protein Function :
May act as a transcriptional corepressor. Has a possible role in the negative regulation of proteins containing WD-40 repeats. May be required for the initiation and maintenance of the differentiated s...[+]

Interactants: Loading ...
Diseases:  External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
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Xenbase Gene ID XB-GENE-868117 XB-GENE-17342204 XB-GENE-868124
Gene Symbol tle5 tle5.L tle5.S
Chromosome Chr01 chr1L Scaffold21
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 733921
379357
398976
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL TrEMBL RefSeq TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tle5 tle5.L tle5.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TLE5 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tle5 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tle5 ZFIN Ensembl
chicken
GEISHA AES Ensembl
fruit fly
worm
WORMBASE
Publications
First Cloning and developmental expression of Xenopus cDNAs encoding the Enhancer of split groucho and related proteins., Gene 1997  
Most Recent A single KH domain in Bicaudal-C links mRNA binding and translational repression functions to maternal development., Development 2019                  
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 2 terms 2 terms
PANTHER tle5
KEGG Pathways
KOG [B] Transducin-like enhancer of split protein (contains WD40 repeats)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks tle5
ORFs aes ORF1 aes.L ORF1 aes.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.13.0


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