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Summary Expression Gene Literature (101) GO Terms (19) Nucleotides (63) Proteins (22) Interactants (196) Wiki
XB-GENEPAGE- 876601

Gene Symbol: gja1

Gene Name: gap junction protein alpha 1

Synonyms: connexin 43 , connexin43 , cx43 , alpha 1 gap junction protein
Add Xenopus synonyms , Nomenclature history


Gene Function: connexon channel component

Protein Function :
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.


Interactants: Loading ...

Disease Ontology Associations: ERYTHROKERATODERMIA VARIABILIS [+]

OMIM Disease Associations: ERYTHROKERATODERMIA VARIABILIS ET PROGRESSIVA; EKVP [+]
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Xenbase Gene ID XB-GENE-876602 XB-GENE-876609 XB-GENE-17334782
Gene Symbol gja1 gja1.L gja1.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq NCBI Nucleotide
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.1 [+] Xl.1109
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 10 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine gja1 gja1.L gja1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GJA1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Gja1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR cx43 cx40.8 ZFIN Ensembl
chicken
GEISHA GJA1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Cloning and expression of a Xenopus embryonic gap junction protein. [Science 1989]
Most recent: Cellular composition and organization of the spinal cord central canal during metamorphosis of the frog Xenopus laevis. [J Comp Neurol 2018]
View All Papers 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontologies
Functional Ontologies tropicalis laevis.L laevis.S
GO 17 terms 7 terms 5 terms
PANTHER gja1
KEGG Pathways K07372 K07372 K07372
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF gja1.L ORF1
Affymetrix 1.0 Str.1.1.S1_at [+] Xl.1109.1.S1_at [+]
Affymetrix 2.0 Xl2.1109.1.S1_at [+]

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556