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Summary Expression Gene Literature (138) GO Terms (10) Nucleotides (45) Proteins (24) Interactants (131) Wiki
XB-GENEPAGE-876705
Gene Symbol:
smad6.2

Gene Name:
SMAD family member 6, gene 2

Synonyms:
Xsmad6 ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction, TGF-beta pathway

Protein Function :


InterPro :
MAD homology MH1 , SMAD FHA dom sf , SMAD MH1 sf , SMAD dom Dwarfin-type [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
aortic valve stenosis

OMIM:
AORTIC VALVE DISEASE 2; AOVD2 [+]

External Links:
 
Xenbase Gene ID XB-GENE-876706 XB-GENE-6488044 XB-GENE-17330795
Gene Symbol smad6.2 smad6.2.L smad6.2.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100492635
108699473
108700695
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine smad6.2 smad6.2.L smad6.2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SMAD6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Smad6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Smad6 Ensembl
zebrafish
ZFIN, AGR smad6a ZFIN Ensembl
chicken
GEISHA SMAD6 Ensembl
fruit fly
worm
Publications
First Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling., Nature 1997  
Most Recent Coordinated regulation of the dorsal-ventral and anterior-posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14., Dev Growth Differ 2018            
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 7 terms 0 term
PANTHER smad6.2
KEGG Pathways K04677 K04677
KOG [TK] TGFbeta receptor signaling protein SMAD and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks smad6.2
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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