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Summary Expression Gene Literature (38) GO Terms (6) Nucleotides (2439) Proteins (47) Interactants (622) Wiki
XB-GENEPAGE-876928
Gene Symbol:
krt8.1

Gene Name:
keratin 8, gene 1

Synonyms:
keratin8 , XCK1 , CK1 , krt8 ( Add synonyms , Nomenclature history )

Gene Function:
fibrous structural protein

Protein Function :
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.


InterPro :
Sec1-like sf , Sec1-like , Sec-1-like dom2 , MHC I/II-like Ag-recog [+]

Interactants:
Loading ...

Diseases: 


OMIM:
CIRRHOSIS, FAMILIAL

External Links:
1/4
 
Xenbase Gene ID XB-GENE-876929 XB-GENE-17339330 XB-GENE-876943
Gene Symbol krt8.1 krt8.1.L krt8.1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 431676
108708656
380217
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine krt8.1 krt8.1.L krt8.1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards KRT8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Krt8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Krt8 Ensembl
zebrafish
ZFIN, AGR krt8 ZFIN Ensembl
chicken
GEISHA KRT8 Ensembl
fruit fly
Publications
First Cloning of cDNA and amino acid sequence of a cytokeratin expressed in oocytes of Xenopus laevis., Proc Natl Acad Sci U S A 1986  
Most Recent The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier., Elife 2019                      
All View All Papers 6 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 3 terms 2 terms 5 terms
PANTHER krt8.1
KEGG Pathways K07605 K07605 K07605
KOG [DY] Nuclear envelope protein lamin, intermediate filament superfamily
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks krt8.1
Morpholinos krt8.1 MO1 , krt8.1 MO2
ORFs krt8 ORF1 krt8.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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