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Summary Expression Gene Literature (28) GO Terms (18) Nucleotides (197) Proteins (29) Interactants (632) Wiki
XB-GENEPAGE-919852
Gene Symbol: cxcl12

Gene Name: C-X-C motif chemokine ligand 12

Synonyms: sdf-1 , stromal-derived factor 1 , xSDF-1 , xSDF-1alpha , sdf1 ( Add synonyms , Nomenclature history )

Gene Function: small cytokine

Protein Function :
Chemoattractant (PubMed:11859124). Activates the C-X-C chemokine receptor cxcr4 to induce a rapid and transient rise in the level of intracellular calcium ions, and chemotaxis (PubMed:11859124). Signal...[+]

Interactants: Loading ...
Disease Ontology: acquired immunodeficiency syndrome

OMIM Diseases: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO

 
Xenbase Gene ID XB-GENE-919853 XB-GENE-6077780 XB-GENE-17333076
Gene Symbol cxcl12 cxcl12.L cxcl12.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq TrEMBL Swiss-Prot RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine cxcl12 cxcl12.L cxcl12.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CXCL12 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Cxcl12 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR cxcl12b cxcl12a ZFIN Ensembl
chicken
GEISHA CXCL12 Ensembl
fruit fly
worm
WORMBASE
Publications
First Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene., Genomics 1995  
Most Recent In vivo topology converts competition for cell-matrix adhesion into directional migration., Nat Commun 2019                      
All View All Papers 8 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 14 terms 0 term
PANTHER cxcl12
KEGG Pathways K10031 K10031
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino cxcl12 MO1 , cxcl12 MO2 cxcl12 MO1 , cxcl12 MO2 cxcl12 MO1 , cxcl12 MO2
ORF cxcl12 ORF1 cxcl12.L ORF1
Affymetrix 1.0 Str.28913.1.A1_at Xl.4813.1.S1_at
Affymetrix 2.0 Xl2.4813.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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