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Summary Expression Gene Literature (30) GO Terms (24) Nucleotides (215) Proteins (37) Interactants (652) Wiki
XB-GENEPAGE-919852
Gene Symbol:
cxcl12

Gene Name:
C-X-C motif chemokine ligand 12

Synonyms:
sdf-1 , stromal-derived factor 1 , xSDF-1 , xSDF-1alpha , sdf1 ( Add synonyms , Nomenclature history )

Gene Function:
small cytokine

Protein Function :
Chemoattractant (PubMed:11859124). Activates the C-X-C chemokine receptor cxcr4 to induce a rapid and transient rise in the level of intracellular calcium ions, and chemotaxis (PubMed:11859124). Signal...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
acquired immunodeficiency syndrome

OMIM:
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO

External Links:
 
Xenbase Gene ID XB-GENE-919853 XB-GENE-6077780 XB-GENE-17333076
Gene Symbol cxcl12 cxcl12.L cxcl12.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 548481
399030
108697525
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cxcl12 cxcl12.L cxcl12.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CXCL12 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cxcl12 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cxcl12 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR cxcl12b cxcl12a ZFIN Ensembl
chicken
GEISHA CXCL12 Ensembl
fruit fly
worm
Publications
First Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene., Genomics 1995  
Most Recent In vivo Neural Crest Cell Migration Is Controlled by "Mixotaxis"., Front Physiol 2020      
All View All Papers 8 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 22 terms 14 terms 0 term
PANTHER cxcl12
KEGG Pathways K10031 K10031
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cxcl12
Morpholinos (on-target & off-target) cxcl12 MO2 , cxcl12 MO1 cxcl12 MO1 , cxcl12 MO2 cxcl12 MO1 , cxcl12 MO2
ORFs cxcl12 ORF1 cxcl12.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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