Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (46) GO Terms (6) Nucleotides (77) Proteins (33) Interactants (248) Wiki
XB-GENEPAGE-919964
Gene Symbol:
des.2

Gene Name:
desmin, gene 2

Synonyms:
desmin-like ( Add synonyms , Nomenclature history )

Gene Function:
intermediate filament

Protein Function :
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).


InterPro :
Tgfb1i1/Leupaxin/TGFB1I1 , Znf LIM , SKP1/BTB/POZ sf , BTB/POZ dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
myofibrillar myopathy 1 [+]

OMIM:
CARDIOMYOPATHY, DILATED, 1I; CMD1I [+]

External Links:
 
Xenbase Gene ID XB-GENE-919965 XB-GENE-17338516 XB-GENE-919967
Gene Symbol des.2 des.2.L des.2.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100490404
100126634
733312
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein NCBI Protein NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine des.2 des.2.L des.2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DES OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Des MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Des Ensembl
zebrafish
ZFIN, AGR desma ZFIN Ensembl
chicken
GEISHA DES Ensembl
fruit fly
worm
Publications
First Tetanic hyperpolarization of single medullated nerve fibers in sodium and lithium., Am J Physiol 1976  
Most Recent Motilin- and ghrelin-induced contractions in isolated gastrointestinal strips from three species of frogs., Gen Comp Endocrinol 2021  
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 6 terms 0 term 0 term
PANTHER des.2
KEGG Pathways
KOG [DY] Nuclear envelope protein lamin, intermediate filament superfamily
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks des.2
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info