Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (5) GO Terms (19) Nucleotides (187) Proteins (28) Interactants (306) Wiki
XB-GENEPAGE-920278
Gene Symbol:
fat1

Gene Name:
FAT atypical cadherin 1

Synonyms:
me5 , cdhf7 ( Add synonyms , Nomenclature history )

Gene Function:
cadherin/protocadherin superfamily, cell adhesion/signal transduction

Protein Function :
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondri...[+]



Interactants:
Loading ...

Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-920279 XB-GENE-6486349 XB-GENE-17333527
Gene Symbol fat1 fat1.L fat1.S
Chromosome Chr01 Scaffold12834
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 6.0
CDS Gene model
Entrez Gene 100489070
mRNA NCBI Nucleotide
Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine fat1 fat1.L fat1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FAT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fat1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fat1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR fat1a fat1b ZFIN Ensembl
chicken
GEISHA FAT1 Ensembl
fruit fly
worm
Publications
First The loop C region of the murine 5-HT3A receptor contributes to the differential actions of 5-hydroxytryptamine and m-chlorophenylbiguanide., Biochemistry 2005  
Most Recent Quantitative Proteomics After Spinal Cord Injury (SCI) in a Regenerative and a Nonregenerative Stage in the Frog Xenopus laevis., Mol Cell Proteomics 2018                  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 0 term 0 term
PANTHER fat1
KEGG Pathways
KOG [T] Uncharacterized conserved protein, contains laminin, cadherin and EGF domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks fat1
Clones Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556