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XB-GENEPAGE-920732
Gene Symbol:
insr
Gene Name: insulin receptor
Synonyms:
Xe-InsR
,
insulin receptor
,
hhf5
,
cd220
,
XTK1
,
XTK1a
,
XTK1b
( Gene Function: growth factor receptor, contains protein kinase domain Protein Function
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Receptor tyrosine kinase which mediates actions of insulin. May be required for forelimb regeneration.
Interactants:
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Diseases: Disease Ontology:
Donohue syndrome
OMIM:
DIABETES MELLITUS, INSULIN-RESISTANT, WITH ACANTHOSIS NIGRICANS
External Links:
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Xenbase Gene ID | XB-GENE-920733 | XB-GENE-920741 | XB-GENE-17333862 | |||||
Gene Symbol | insr | insr.L | insr.S | Chromosome | Chr1 | chr1L | Scaffold21 | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100492718
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398006
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100158430
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | insr | insr.L | insr.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells., Proc Natl Acad Sci U S A 1985 |
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Most Recent |
Beneficial actions of the [A14K] analog of the frog skin peptide PGLa-AM1 in mice with obesity and degenerative diabetes: A mechanistic study., Peptides 2021 |
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All | View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 21 terms | 16 terms | 5 terms | |||||
PANTHER | insr | |||||||
KEGG Pathways | K04527 | K04527 | K04527 | |||||
KOG |
[T] Insulin/growth factor receptor (contains protein kinase domain)
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | insr | |||||||
Antibodies | Insr Ab1 | Insr Ab1 | ||||||
Morpholinos (on-target & off-target) | insr MO1 | insr MO1 | insr MO1 | |||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
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