Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (277) GO Terms (13) Nucleotides (281) Proteins (51) Interactants (755) Wiki
XB-GENEPAGE-921634
Gene Symbol:
gnao1

Gene Name:
G protein subunit alpha o1

Synonyms:
XGalpha01 , gao , ga0 , g0alpha , g0a , Go ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction

Protein Function :
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear.


InterPro :
Palmitoyltrfase DHHC , Gprotein alpha su , GproteinA insert , Gprotein alpha I [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Ohtahara syndrome

OMIM:
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 17; EIEE17 [+]

External Links:
 
Xenbase Gene ID XB-GENE-921635 XB-GENE-921656 XB-GENE-17340914
Gene Symbol gnao1 gnao1.L gnao1.S
Chromosome Chr04 Scaffold61186 chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model
Entrez Gene 549749
394423
397896
mRNA RefSeq RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gnao1 gnao1.L gnao1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GNAO1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gnao1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gnao1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR gnao1a gnao1b ZFIN Ensembl
chicken
GEISHA GNAO1 Ensembl
fruit fly
worm
Publications
First Biochemical data on subtotally hypophysectomized Xenopus laevis (Daudin) adult specimens treated or not with prolactin., Arch Sci Biol (Bologna) 1976  
Most Recent Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Development 2018                          
All View All Papers 7 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 6 terms 5 terms
PANTHER gnao1
KEGG Pathways K04534 K04534 K04534
KOG [DT] G-protein alpha subunit (small G protein superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gnao1
Antibodies Gnao1 Ab1 , Gnao1 Ab3 Gnao1 Ab3
ORFs gnao1 ORF1 gnao1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556