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Summary Expression Gene Literature (46) GO Terms (14) Nucleotides (262) Proteins (50) Interactants (424) Wiki
XB-GENEPAGE-941406
Gene Symbol:
pxn

Gene Name:
paxillin

Synonyms:
paxillin ( Add synonyms , Nomenclature history )

Gene Function:
Adaptor protein Enigma and related PDZ-LIM proteins

Protein Function :
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).


InterPro :
Tgfb1i1/Leupaxin/TGFB1I1 , Znf LIM , DUF2428 death-receptor-like , ARM-type fold [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-941407 XB-GENE-17336978 XB-GENE-941410
Gene Symbol pxn pxn.L pxn.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100216044
108716013
397826
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pxn pxn.L pxn.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PXN OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pxn MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pxn Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR pxna pxnb ZFIN Ensembl
chicken
GEISHA TGFB1I1 Ensembl
fruit fly
FLYBASE Pxn Ensembl
worm
Publications
First Localization of paxillin, a focal adhesion protein, to smooth muscle dense plaques, and the myotendinous and neuromuscular junctions of skeletal muscle., Exp Cell Res 1991  
Most Recent Ectoderm to mesoderm transition by down-regulation of actomyosin contractility., PLoS Biol 2021                                              
All View All Papers 6 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 5 terms 5 terms
PANTHER pxn
KEGG Pathways K05760 K05760
KOG [TZ] Adaptor protein Enigma and related PDZ-LIM proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pxn
Antibodies Pxn Ab1 , Pxn Ab2 , Pxn Ab4 , Pxn Ab5 Pxn Ab4 , Pxn Ab2 , Pxn Ab5 Pxn Ab1 , Pxn Ab2 , Pxn Ab4 , Pxn Ab5
ORFs pxn.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info