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Summary Expression Gene Literature (163) GO Terms (20) Nucleotides (180) Proteins (39) Interactants (549) Wiki
XB-GENEPAGE-941785
Gene Symbol:
gemin2

Gene Name:
gem nuclear organelle associated protein 2

Synonyms:
sip1-delta , sip1 , SMN interacting protein 1 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular ...[+]


InterPro :
Reg factor effector dom sf , SOUL haem-bd , GEMIN2 , Gemin2/Brr1 [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-941786 XB-GENE-17346289 XB-GENE-941790
Gene Symbol gemin2 gemin2.L gemin2.S
Chromosome Chr8 chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100124782
494588
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gemin2 gemin2.L gemin2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GEMIN2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gemin2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gemin2 Ensembl
zebrafish
ZFIN, AGR gemin2 ZFIN Ensembl
chicken
GEISHA GEMIN2 Ensembl
fruit fly
worm
Publications
First The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis., Cell 1997  
Most Recent Cdc2-like kinase 2 (Clk2) promotes early neural development in Xenopus embryos., Dev Growth Differ 2019                                
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 0 term 8 terms
PANTHER gemin2
KEGG Pathways K13130 K13130
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gemin2
ORFs gemin2 ORF1 gemin2.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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