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Summary Expression Gene Literature (34) GO Terms (4) Nucleotides (76) Proteins (35) Interactants (164) Wiki
XB-GENEPAGE-943714
Gene Symbol:
mxd1

Gene Name:
MAX dimerization protein 1

Synonyms:
Mad1 , xmad1 ( Add synonyms , Nomenclature history )

Gene Function:
transcription factor

Protein Function :
Component of a transcriptional repressor complex together with MAX. In complex with MAX binds to the core DNA sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing with MYC fo...[+]


InterPro :
MXD1 , HLH DNA-bd sf , bHLH dom

Interactants:
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Diseases: 


External Links:
1/6
 
Xenbase Gene ID XB-GENE-943715 XB-GENE-943720 XB-GENE-17339888
Gene Symbol mxd1 mxd1.L mxd1.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 779675
779097
108712772
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine mxd1 mxd1.L mxd1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MXD1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mxd1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mxd1 Ensembl
zebrafish
ZFIN, AGR mxd1 ZFIN Ensembl
chicken
GEISHA MXD1 Ensembl
fruit fly
worm
Publications
First Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily., Cell 1996  
Most Recent The Spindle Assembly Checkpoint Functions during Early Development in Non-Chordate Embryos., Cells 2020                
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 4 terms 2 terms
PANTHER mxd1
KEGG Pathways K09114 K09114
KOG [K] Upstream transcription factor 2/L-myc-2 protein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks mxd1
ORFs mxd1 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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