fkbp1b Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-944315

[provisional- machine annotated only]

Gene Symbol: fkbp1b [Predicted: Source is Human Entrez Gene]

Gene Name: FK506 binding protein 1B, 12.6 kDa [Predicted: Source is Human Entrez Gene]

Synonyms: otk4, fkbp1l, pkbp1l, PPIase, fkbp12.6, xfkbp1b Add Xenopus synonyms

Gene Function: FKBP-type peptidyl-prolyl cis-trans isomerase

Interactants: fkbp1a(7) , fkbp4(6) , pin1(3) , cdc25c(2) , rasgrf1(2) , wee1(2) , bmp4(1) View All

XB-GENE-944316

XB-GENE-6077914

Molecules	tropicalis	laevis
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
	Entrez Gene	Entrez Gene
mRNA	Refseq >NM_001103022\|Xenopus (Silurana) tropicalis FK506 binding protein 1B, 12.6 kDa (fkbp1b), mRNA GCGGCGAGCAGAGAAGCAGGAAGCGGAGAATAGCGAAGACAGGCAGCCATGGGAGTGGACCTGGAAACTATCTCACCCGGAGACGGTAGGACATTTCCAAAGAAGGGCCAAACATGTGTAGTCCATTACACAGGGATGTTACAGAACGGGAGGAAGTTTGACTCATCCAGAGACCGAAACAAGCCTTTCAAGTTCAAGATTGGGCGTCAGGAAGTGATCAAAGGCTGGGAGGAAGGAGTTGCACAGATGAGTTTGGGCCAGAGAGCAAAGCTGACCTGCTCCCCTGATGTTGCCTACGGAGCCACAGGGCACCCCGGAGTCATCCCTCCCAATGCCACTCTGATCTTCGATGTTGAGTTAATACGGATAGAGTAGACTACGTCTGGAGAAGGGCCGGCCAACGATCTCCAAACACTACCGCCATCCACTTCCTTAAGAGACCTCCTTACTGCTGAAGAAAACCTTTCCCACCTAGACTCCAACAGCAAGAGGGGGAACAAGTCTTCATATTTAACCCTAGTGCTGCCAGAGCAGATAGCTAAGGGGAACATGACTGGCAACAAGGGGTTCTAGGAAATGTAACAGGGCTACCTTTAGGTGAAGAGCAGGAGACCTGCGGTGCTCAGGTCTTTGTATTCCAACTAAATATATTAATGTAGTTCCCATACTATTCATCACCAGTAAAGGGACAACTGACATTGTGGTTTTATCCTATTCATTTTGTTATTACTTAATTGTAGTGGTGAAGTGAAAGCAGAGACCGCAGGTGGCCTGCCACCTTGAAGTAGCCCAACCGTCTGCAGCTAAAAGTGGCAGTCCTTCATTATGGGTGTGAATCCAATTGGCCATCCCAAGAGCAGAGTGAAATCCATGAGTGCACTTGTCCATGAATAGTCTGATATTGGGAGTTGCCCACAACTTGTACTTTCTGCTGGTTTAGGAAGGGTTTGTACCAAGCCATATACAGTATGAAAGGTGATGTCCTTCATATATGTCCTACAGAGTTTGCCTCCAAGTCCACTTGGCTGACATCTTTCTGTTCTATCCTTAGTATATTTGGGAGTTGTACATGTAGTCAAGAAATATGGAGCATTTTTATGTTTCTTTCAATGGCACAAGACCCTTAGACATATATTGATATATACAGACACTAGCAAGTTGAGCTTAGAGAATGGGCGGAGCTCCAGGGCTGTTTTTATATAATTCCAGGGCCTGGTTCCAAATAGGAAAGGGTATCATTGTCAGCTTCTTGCCCTACTGATCCTGACTTGCTTTGCCTCTCCACACTCTGCTCGGCCTATCTGTGTTCGAGGCCCTTGTCAGCTGGCCCTTTTTGGAATCCACCACAAGGACTGCCCCTTTAAGATGCTCAAAGCAAAAGAATCAAGCTTTGTTTCAGATAAGCCCACATCTACGATTCTTCCCCTGATCTTGGCCTCTGCCCAGGAGAAAAAAAAAAAATCTACCCCACAGCTAGGGGTAAACACATTGCTGTTATTGTAATTTTACTTTTTTTAAAAGTTGTGTCTGTGTTTTTGTCTTGAAGCTTAAAGCCTTGTTGCTTTCCAGCAAAACAAAATGGGGAAGGTGAGGGGTGGGGGTTGCAGAATGGAATAAACAGCAAGACTGGCTACAGCACTCTAAGTTGTACATTTTCTATAAGCCTTCCACTGCCGGAAGGGCCAGCCTTGGCTCACAGGGCCACCGTAGGGCCCCTCCGGCAGGGAGGCGGGGTTTTAATTTGCATGTGACATGATTCACACTTATAAATCAAAAGAATGATCTCAAAAAAAAAAAAAAA	Refseq >NM_001090116\|Xenopus laevis FK506 binding protein 1B, 12.6 kDa (fkbp1b), mRNA CCTTGTGCCAGAGCCTGGGAAGCGGCGAGCAGAGAAGCAGGAAGCGAAGAATTGCTCCGAGCGACAGCCATGGGAGTGGATCTGGAAACTATCTCACCTGGAGACGGTAGGACATTTCCAAAGAAGGGCCAAACATGTGTAGTCCATTACACAGGGATGTTAACGAGTGGAAAGACGTTTGACTCGTCCAGAGACCGGAACAAGCCTTTCAAGTTCAAGATTGGGAGGCAGGAAGTGATCAAAGGCTGGGAGGAAGGAGTTGCACAGATGAGTGTGGGCCAGAGAGCAAAGCTAACCTGCTCCCCTGATGTTGCCTATGGAGCCACAGGGCACCCCGGAGTCATTCCTCCCAATGCCGTTCTGATCTTCGATGTTGAGTTAATACGGATAGAGTAGACTACGTCTGGAGAAGGGCCGGCCAACGATCTCCAAACACCACCACCATCCACTTCCTTATGAGACCTCCTCACTGCTGAAGAAAACGTTTCACATGTAGACTCCAACAGTGAGAGGGGGAACATGTCTTCATATTAAACCCTAGTGCTGCCAGAGCAGATAGCTAAGGGGAACATGACTGGCAACAAAGGGTTATAGGAATCGTCACAAGGCTACCTTTAGGTGAAGAGCAGAAGACCTGCGGTGCTCAAGTTTTTGTATTCCAACCAAATATGTTAACATAGTTCCAATAGTACTGATTATATGTAAAGGCACAAAGTGAGAATGGTGTGTTTTTCCCCAATAACATTTTTTGCCATTTGTCTTTACTAAATTGTAGTGGTGAAGTGAAAACAGAGCTCGCAGGCAGCCTGCCATCTAAAAGTAGCCCGATCTTCTGCACCTAAAAGTGGCAGTCCATTATGTGCGTGAATCCAATTGGCTAAGGGCAATGGGACATCAGTCAATGCAGTTCTCAATGAAAAGTTTAATATTGTCAATTGCCCACTACTGGTTTAAGAAAGGGTTTATACCAAGTTATGTACAATATAAAATAATAATGAGGTGATGTCCTTCATTTATGTGCTACAGAGATCACCTAAACGTGGTGTCCATTTTGTTGAAGATCCAAGTCTTGCTTTATTATTGACAGTGCTTTTTGGGAATTGTGGATCATTGTTATGTTTCCTCTTATGGCACAAGACCATTATATATAAAGATATAGATGCACACATTAGTAAGTTGAGCTTGGTGCATGGAAGGAGTGCTAGGGCAGGGCCTGGTGTAAACCAGAACAGTCAGTGGGTGCTTCACCAACAACTGAAGGGTGTCAATGTCATCTTCTTGCTTTACTGATCCCATGTTGCTCTGCTTGGCCTCACTGAGGCCCTTGGCAACTGGCCCTTTTTGGACTGCGCTATGAGGACTGCCCCTTTTAAGATGCTCAGAGAAAACTAACTGACCTCTGTTTCCAATAAACCCACATCTGCGATTCTTCCCTGATCTTGGCCTCTTCCCAGGAGAAAAAGAAATCTACCCCGCAGCTAGGGGTAAACACATTGCTGTTATTGTCATTTTACTTTTTTAAAAGTTGTGTCTGTGTTTTTGTCTTGAAGCTTAAAGCCTTGTTGCTTTCCAGCAAAACAAATTGGGGAAGGCGGGTTGGGGGCGGGGCTGGGGATTGGGAAAATACAGCAAGTCTGGCTACAGCATTCTTAAGTTGTACATTTTCTGTAAGCCTTACACTGCTTGAAGGGCCGGCCTTGGCTCACCGAGCTGTTGTTTGGCCCCTCCGGCAGGGAGATGGGGTTTTAATTTGCATGTGACATAATTCACAATTATAAATCAAAAGAATGATCTAAAAAAAAAAAAAAAA
Protein	Refseq >NP_001096492\|FK506 binding protein 1B, 12.6 kDa [Xenopus (Silurana) tropicalis] MGVDLETISPGDGRTFPKKGQTCVVHYTGMLQNGRKFDSSRDRNKPFKFKIGRQEVIKGWEEGVAQMSLGQRAKLTCSPDVAYGATGHPGVIPPNATLIFDVELIRIE	Refseq >NP_001083585\|FK506 binding protein 1B, 12.6 kDa [Xenopus laevis] MGVDLETISPGDGRTFPKKGQTCVVHYTGMLTSGKTFDSSRDRNKPFKFKIGRQEVIKGWEEGVAQMSVGQRAKLTCSPDVAYGATGHPGVIPPNAVLIFDVELIRIE

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI Ensembl UCSC	Xenbase

Synteny	Metazome

Expression	tropicalis	laevis
UniGene	Str.49198 [+] Str.60271 Str.60832	Xl.67363
Unigene EST Profile	EST Profile	EST Profile
GEO data		GEO
Images	0 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	FKBP1B
mouse	MGI	Fkbp1b	All(6) Targeted, knock Out(3) Targeted, other(3)
zebrafish	ZFIN	fkbp1b

Publications
First:		The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. [Genes Dev 1998]
Most recent:		Peptidyl-prolyl cis-trans isomerase xFKBP1B induces ectopic secondary axis and is involved in eye formation during Xenopus embryogenesis. [Dev Growth Differ 2011]
		View All Papers

Functional Ontologies
GO: Molecular:		FK506-sensitive peptidyl-prolyl cis-trans isomerase cyclophilin cyclophilin-type peptidyl-prolyl cis-trans isomerase activity More[+] peptidyl-prolyl cis-trans isomerase activity
Biological:		protein folding
Cellular Component:
EC:		peptidylprolyl isomerase
KOG:		[O] FKBP-type peptidyl-prolyl cis-trans isomerase (alt_id KOG:0544)

Reagents	tropicalis	laevis
Clones	open biosystems	open biosystems
	geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0	Str.24398.1.S1_at [+] Str.28973.2.S1_at Str.28973.1.A1_at Str.44158.1.A1_at Str.44158.1.A1_x_at
Affymetrix 2.0		Xl2.8574.1.S1_at [+] Xl2.34720.1.S1_x_at

Symbol legend[+]