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Summary Expression Gene Literature (2) GO Terms (11) Nucleotides (45) Proteins (16) Interactants (132) Wiki
XB-GENEPAGE- 944425

Gene Symbol: gfi1b

Gene Name: growth factor independent 1B transcription repressor

Synonyms: znf544 , zinc finger protein 544
Add Xenopus synonyms , Nomenclature history


Gene Function: zinc finger, C2H2 type

Protein Function :
Essential transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages. Alters histone methylation by recruiting histone methyltransferase to target ...[+]


Interactants: Loading ...

Disease Ontology:
   PLATELET-TYPE BLEEDING DISORDER 17

OMIM Diseases:
   BLEEDING DISORDER, PLATELET-TYPE, 17; BDPLT17
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Xenbase Gene ID XB-GENE-944426 XB-GENE-944429 XB-GENE-17334706
Gene Symbol gfi1b gfi1b.L gfi1b.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.49110 [+] Xl.48425
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 52 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine gfi1b gfi1b.L gfi1b.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GFI1B OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Gfi1b MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR gfi1b ZFIN Ensembl
chicken
GEISHA GFI1B Ensembl
fruit fly
worm
WORMBASE
Publications
First: HoxA3 is an apical regulator of haemogenic endothelium. [Nat Cell Biol 2011]
Most recent: VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus. [Development 2013]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 2 terms 10 terms 0 term
PANTHER gfi1b
KEGG Pathways K09223
KOG [K] C2H2-type Zn-finger protein
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF gfi1b.L ORF1
Affymetrix 1.0 Str.49110.1.S1_at [+]
Affymetrix 2.0 Xl2.48425.1.S1_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556