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Summary Expression Gene Literature (13) GO Terms (17) Nucleotides (334) Proteins (25) Interactants (126) Wiki
XB-GENEPAGE-945387
Gene Symbol: adam10

Gene Name: ADAM metallopeptidase domain 10

Synonyms: xadam10 , kuz , ad10 , madm , cd156c , kuzbanian ( Add synonyms , Nomenclature history )

Gene Function: Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases

Protein Function :
Controls the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis.

Interactants: Loading ...
Disease Ontology: Alzheimer's disease 18

OMIM Diseases: ALZHEIMER DISEASE 18; AD18 [+]

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Xenbase Gene ID XB-GENE-945388 XB-GENE-17330822 XB-GENE-945394
Gene Symbol adam10 adam10.L adam10.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine adam10 adam10.L adam10.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ADAM10 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Adam10 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR adam10b adam10a ZFIN Ensembl
chicken
GEISHA ADAM10 Ensembl
fruit fly
worm
WORMBASE
Publications
First Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis., Cell 1997    
Most Recent GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration., Mol Biol Cell 2014                                      
All View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 0 term 16 terms
PANTHER adam10
KEGG Pathways K06704 K06704
KOG [W] Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Adam10 Ab1 Adam10 Ab1 Adam10 Ab1
Morpholino adam10 MO1 adam10 MO1 adam10 MO1
ORF adam10.S ORF1
Affymetrix 1.0 Str.5883.1.S1_at [+] Xl.7065.1.S1_at [+]
Affymetrix 2.0 Xl2.45695.1.S2_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.0


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