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Summary Expression Gene Literature (13) GO Terms (21) Nucleotides (344) Proteins (29) Interactants (126) Wiki
XB-GENEPAGE-945387
Gene Symbol: adam10

Gene Name: ADAM metallopeptidase domain 10

Synonyms: xadam10 , kuz , ad10 , madm , cd156c , kuzbanian ( Add synonyms , Nomenclature history )

Gene Function: Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases

Protein Function :
Controls the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis.

Interactants: Loading ...
Diseases:  Disease Ontology: Alzheimer's disease 18

OMIM: ALZHEIMER DISEASE 18; AD18 [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
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Xenbase Gene ID XB-GENE-945388 XB-GENE-17330822 XB-GENE-945394
Gene Symbol adam10 adam10.L adam10.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 733451
399187
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine adam10 adam10.L adam10.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ADAM10 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Adam10 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR adam10b adam10a ZFIN Ensembl
chicken
GEISHA ADAM10 Ensembl
fruit fly
worm
WORMBASE
Publications
First Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis., Cell 1997    
Most Recent GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration., Mol Biol Cell 2014                                      
All View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 0 term 16 terms
PANTHER adam10
KEGG Pathways K06704 K06704
KOG [W] Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks adam10
Antibodies Adam10 Ab1 Adam10 Ab1 Adam10 Ab1
Morpholinos adam10 MO1 adam10 MO1 adam10 MO1
ORFs adam10.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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