Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (0) GO Terms (8) Nucleotides (108) Proteins (36) Interactants (91) Wiki
XB-GENEPAGE-946206
Gene Symbol:
tollip

Gene Name:
toll interacting protein

Synonyms:
IL-1RAcPIP , tollip-b , tollip-a ( Add synonyms , Nomenclature history )

Gene Function:
Predicted Ca2+-dependent phospholipid-binding protein

Protein Function :
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family...[+]


InterPro :
Homeobox metazoa , Homeobox CS , Homeobox dom , Homeobox-like sf [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-946207 XB-GENE-946212 XB-GENE-6255027
Gene Symbol tollip tollip.L tollip.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448770
443846
734800
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tollip tollip.L tollip.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards TOLLIP OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tollip MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tollip Ensembl
zebrafish
ZFIN, AGR tollip ZFIN Ensembl
chicken
GEISHA TOLLIP Ensembl
fruit fly
Publications
First
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 6 terms 6 terms
PANTHER tollip
KEGG Pathways K05402 K05402 K05402
KOG [R] Predicted Ca2+-dependent phospholipid-binding protein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tollip
ORFs tollip ORF1 tollip.L ORF1 tollip.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info