mad2l1 Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-947152

[provisional- machine annotated only]

Gene Symbol: mad2l1 [Predicted: Source is Human Entrez Gene]

Gene Name: MAD2 mitotic arrest deficient-like 1 [Predicted: Source is Human Entrez Gene]

Synonyms: mad2, XMad2 Add Xenopus synonyms

Gene Function: Spindle assembly checkpoint protein

Interactants: cdc20(19) , mxd1(19) , bub1(10) , cenpe(10) , bub3(9) , plk1(5) , rps27(5) View All

XB-GENE-947153

XB-GENE-947158

Molecules	tropicalis	laevis
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
	Entrez Gene	Entrez Gene
mRNA	Refseq >NM_001103058\|Xenopus (Silurana) tropicalis MAD2 mitotic arrest deficient-like 1 (mad2l1), mRNA GACCTGAAAACTTTTGGAACCAATTCAGTTTTACAAGAAGGGTCCGATGGCCGGTCAGCTAACACGTGAAGGGATTACCCTGAAGGGTAGCGCTGAAATCGTGTCGGAGTTTTTCTTTTGTGGCATCAATAGTATTTTATATCAGCGTGGGATTTATCCATCAGAAACGTTCACACGTATCCAGAAGTATGGACTTACACTGCTACTCACTACAGACCCAGGGCTGAAAGAGTATTTAAATAAAGTTACCGATCAGCTTAAAGATTGGTTGTACAAATGCCAGGTACAGAAGCTTGTGGTTGTGATAACAAGTATCGACAGCAATGAAATTCTTGAACGCTGGCAGTTTGACATAGAGTGTGACAAAACTGTGAAAGATGGTATTGTTCGTGAAAAGTCGCAAAAGGTTATTCAAGAAGAAATTCGATCAGTTATAAGGCAAATTACTGCCACTGTAACTTTCCTTCCTTTGCTGGAAACAGCATGTGCCTTTGACTTGCTGATATATACAGATAAAGACTTGGAAGTCCCTGAGAAATGGGAGGAATCTGGTCCTCAGTTTGTGTCCAACTCTGAAGAGGTCCGCCTGCGTTCATTTACAACAACTATTCACAAAGTAAATAGTATGGTGGCATACAAAAAGATAGACACTTGCTAAGAACCTGAGATATCAGTGTTGTATAGAATGCTGCATTTGAGTCTTTTAAAGAAATCCTTTATATTGTTTCATACAAATAGTTTTATGAAACTGTCCCTAGATCAAAATAGGATTGAATTACTGTCAAGGATATACTGTGTGCAGATAAAACAATAAATTGCAAAGGGAGGGGTGACGGGGTGAAAGCCCTTGGTTTAAACCCAGGTATGTTAATATGATTAAGTATAACTGTTACTAAAAAGTCTCCCTCAAGTTCTTAAATCCTGACTTGTTCTTTTTGCTATAAGGCATAATAGCCCCCAGGTATGATTAAATTCATAAGTCTTGCAGTACCATTTTAGGGCTTTGTGCTTTTTAAGTTGTGCTATGTTAACAATTAAAATATGTATTTAAAATGTTACTAGGACTAGGCTGCAGCTAGTTATGTGGGCTGAGGTTTTTATGTACCTTGTTTAAAACTAGGGTTTTGTGATAAACTCTGCTTACAGATCAGCTATATTTCTCTTTTAAAGTCTTTATTCTGCCTCAGCTTCCTAAAATTTAATTTAAAAAAATGCCTTCTAAAAGTGATACAACCCTATGAAGCATATTGACCTTGCACAAAGAATCTATGAACATTAAGCATCTAACAATGTTTTTGAAAATTTATACAATCTTAGAATTTAAGCAAAATTATCTATAAACAGCATATGTGAAGATTTTAGGTGTGTAAATTGAGCTGTTGTATATGACTGCTTTCTTTGTTTTTTTTTTGTGTTGTATCACTGTCAACTTGTCTGTTTCTATTCCTTTTATAAAATAAAGTATTCCTGAATAATTAAAAAAAAAAAAAAA	Refseq >NM_001087272\|Xenopus laevis MAD2 mitotic arrest deficient-like 1 (mad2l1), mRNA GTAGAAGGCGCGTTGTTACTCGCAGAGTCTGAACGGGTTTGGAACCTATTCCGTTTAGGAAAGTGAGTTCGATGGCGGGGCAGCTAACACGTGAAGGGATTACCCTGAAGGGCAGCGCGGAAATCGTATCAGAGTTTTTCTTTTGTGGCATCAATAGTATTTTATATCAGCGTGGGATTTATCCATCAGAAACATTCACACGTATCCAGAAGTATGGGCTCACACTGCTAGTCTCTACAGACCCAGCACTAAAAGAGTATTTAAACAAAGTTACAGATCAGCTTAAAGATTGGTTGTACAAATGCCAAGTACAGAAGCTTGTGGTTGTGATTACAAGTATTGACAGCAATGAAATTCTTGAACGTTGGCAATTTGATATAGAGTGTGACAAAACTGTGAAAGACGGCATTGTTCGTGAAAAATCACAAAAGGTTATTCAGGAAGAAATTCGATCAGTTATAAGGCAGATTACTGCTACTGTAACTTTTCTTCCTTTGCTGGAAACCGCATGTGCTTTTGACTTGCTGATATATACAGATAAAGATTTGGAAGTGCCTGAGAAATGGGAGGAATCTGGTCCTCAGTTTGTGTCCAACTCTGAAGAGGTTCGTCTGCGCTCGTTCACAACCACCATCCACAAAGTAAATAGTATGGTGGCATACAAAAAGATAGACACTTTCTAAAAACCTACGATCTTACTTTTATAGAAATCCTTAATGTTAGCTCATATCTAGTTTCATACAAATAGTTTTATGAAATCTGTCCCTAGAAGTTGATTTGCTACATTAAGAAAAAGGATCACATTACTGTCAAGGATACAGTGGCCTTGTTTTTAGTATTGCCTTATACCGTGAAGCAATAAATTGAAAAGGATGGGGGTTTAAACCCAAGTATGTTAAAGGAACAGTTCAGTGTAAAAATAAAAAGTGGGTAAATGGGCTGTGCAGAATTTAAAAAAAAAGTTTCCAATATGGTTGGTTAGCCAAGGATGTAGTGTGTGAAGACTGGAGTTACTGGATGTGTGGCATGGTGGCCAGGACACTACTTCCTGCTTTTCAGCTCTCTAACTCTTGAGTTAGTCAGTGATTTTGAGGGGGGCCACATGGGACATCCTTAGCATGCAGCTCAGATTCAAAAGCAACCGTTATGACCCATGTGCCCCCCCCCCTCAAGTCACTGATTGGTTACTGCCTGGTCACCAATCGGTGGAAACTAAGAGAGCTGTAAAGCAGGAAGTGGTGTTCTGGCTATTGTGTTGCACATCCAGTCACTCCAGCCTTTGTACATTGCATTTTTGGCTAACTAACCATATTGTAAACGTTTTTTATTTTTTCAATTTTGTACATCCTATCTATTTACCCAGTATTTATTTTTACACTGAACAATTCCTTTAATGTGATTTCGTATGACTGTTACCTAATAGTCACCCTCAAGTTCTTAAATCCTGTTTCTTTTGCTGTAAGGGATAATTGCCCCCAACTATGATTCTGTTCATAAGACTTGCAGCACAATTGTAGGGCTCAGTTGTGCTATGTTAATTAAACCATATATTTTACTAGGATTAGGCTGCAGCTAGTGATGTGGGCTGAGGTTTTATTTACCTTGTTTAGAAGTAGGGTTCTAAGATAAACTCTGCTTAGAGATCAAATATTTTTCTCTTTTAATGCCTTTATTCTGCTCGGGTTTCTGATGCTAAATATAAATGTAATTTTTCAAAGTGAAACAACCCTTTGAAGCACATTGACCTTGCACAAAGAATTTAAGTACATTAAGAATCTAACAATTTATCTTCAGAAAATGTGTACATTCTTAGAATATAAGCATAATTATCTAAAAGCAGGATGTGTAAAGATTTTAGGTATGTAAATTGAACTATTGTAAATGTCTTTTTTCTTTTTGTGTTGTATCACTTTCAACTTGTCAGTTCTATTCCTTTTATAAAATAAAATACTTAATAATAAAAAAAAAAAAAAAA
Protein	Refseq >NP_001096528\|MAD2 mitotic arrest deficient-like 1 [Xenopus (Silurana) tropicalis] MAGQLTREGITLKGSAEIVSEFFFCGINSILYQRGIYPSETFTRIQKYGLTLLLTTDPGLKEYLNKVTDQLKDWLYKCQVQKLVVVITSIDSNEILERWQFDIECDKTVKDGIVREKSQKVIQEEIRSVIRQITATVTFLPLLETACAFDLLIYTDKDLEVPEKWEESGPQFVSNSEEVRLRSFTTTIHKVNSMVAYKKIDTC	Refseq >NP_001080741\|MAD2 mitotic arrest deficient-like 1 [Xenopus laevis] MAGQLTREGITLKGSAEIVSEFFFCGINSILYQRGIYPSETFTRIQKYGLTLLVSTDPALKEYLNKVTDQLKDWLYKCQVQKLVVVITSIDSNEILERWQFDIECDKTVKDGIVREKSQKVIQEEIRSVIRQITATVTFLPLLETACAFDLLIYTDKDLEVPEKWEESGPQFVSNSEEVRLRSFTTTIHKVNSMVAYKKIDTF

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI Ensembl UCSC	Xenbase

Synteny	Metazome

Expression	tropicalis	laevis
UniGene	Str.57262	Xl.6479
Unigene EST Profile	EST Profile	EST Profile
GEO data		GEO
Images	0 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	MAD2L1
mouse	MGI	Mad2l1	All(1) Targeted, knock Out(1)
zebrafish	ZFIN	mad2l1

Publications
First:		Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily. [Cell 1996]
Most recent:		Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis. [J Cell Biol 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		DNA-directed DNA polymerase activity alpha DNA polymerase activity beta DNA polymerase activity More[+] delta DNA polymerase activity epsilon DNA polymerase activity eta DNA polymerase activity gamma DNA-directed DNA polymerase activity iota DNA polymerase activity kappa DNA polymerase activity lambda DNA polymerase activity mu DNA polymerase activity nu DNA polymerase activity sigma DNA polymerase activity theta DNA polymerase activity zeta DNA polymerase activity
Biological:
Cellular Component:
EC:		DNA-directed DNA polymerase
KOG:		[DZ] Spindle assembly checkpoint protein

Reagents	tropicalis	laevis
Clones		EXRC - 1 clone(s)
	open biosystems	open biosystems
	geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0	Str.13001.1.S1_at [+] Str.45186.1.A1_at	Xl.6479.1.S1_at [+] Xl.6479.1.S2_at
Affymetrix 2.0		Xl2.6479.1.S2_at [+] Xl2.6479.1.S1_at

Symbol legend[+]