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Summary Expression Gene Literature (5) GO Terms (14) Nucleotides (154) Proteins (28) Interactants (608) Wiki
XB-GENEPAGE-948556
Gene Symbol: ube3a

Gene Name: ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)

Synonyms: ( Add synonyms , Nomenclature history )

Gene Function: E3 ubiquitin protein ligase

Protein Function :
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.

Interactants: Loading ...
Diseases:  Disease Ontology: Angelman syndrome

OMIM: ANGELMAN SYNDROME; AS

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
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Xenbase Gene ID XB-GENE-948557 XB-GENE-17342218 XB-GENE-948562
Gene Symbol ube3a ube3a.L ube3a.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 407881
108708430
380385
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq TrEMBL TrEMBL NCBI Protein TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ube3a ube3a.L ube3a.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards UBE3A OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ube3a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ube3a ZFIN Ensembl
chicken
GEISHA UBE3A Ensembl
fruit fly
FLYBASE Ube3a Ensembl
worm
WORMBASE
Publications
First Altered GABA(A) receptor subunit expression and pharmacology in human Angelman syndrome cortex., Neurosci Lett 2010  
Most Recent Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan., Sci Rep 2018  
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 6 terms 6 terms
PANTHER ube3a
KEGG Pathways K10587 K10587 K10587
KOG [O] E3 ubiquitin protein ligase (alt_id KOG:0941)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ube3a
ORFs ube3a.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.13.0


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