[provisional- machine annotated only] Gene Symbol: snap25 [Predicted: Source is Human Entrez Gene] Gene Name: synaptosomal-associated protein, 25kDa [Predicted: Source is Human Entrez Gene] Synonyms: ric4, sec9, ric-4, snap-25 Add Xenopus synonyms Gene Function: SNAP-25 (synaptosome-associated protein) component of SNARE complex Interactants: stx1a(15) , cacna1b(4) , cacna1c(4) , kcnb1(4) , cav2(3) , ins(3) , cacna1a(2) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016501|Xenopus (Silurana) tropicalis synaptosomal-associated protein, 25kDa (snap25), mRNA TCCCTGCAAATACTGCCTTCAAATAAGGTTGTAGAGTAGCCTTAGAGTCTGGTTACGCCCTACTCACGGCAGGGAGTTTTGTAGGGAGCCCCCTTGTACACAACACATATAGCCGCCATGGCAGACGACGCTGATATGCGCAATGAGCTGGAGGAGATGCAGAGGCGTGCAGACCAGCTGGCCGATGAGTCACTGGAGAGTACCCGCCGTATGCTGCAGTATGTTGAAGGGAGTAAAGATGCTGGTATCAGGACTTTGGTTATGTTGGATGAGCAAGGAGAACAACTGGAACGCATCGAGGAGGGAATGGAACAAATCAATAAGGACATGAAAGAAGCAGAAAAGAATTTGACGGACCTAGGAAAATTCTGTGGTCTTTGTGTCTGTCCATGTAACAAGCTTAAATCCAGTGATGCTTACAAAAAGGCTTGGGGCAATAATCAGGATGGGGTTGTAGCAAGCCAGCCTGCTCGTGTTGTGGATGAGCGTGAGCAGATGGCCATAAGTGGAGGCTTTGTCCGTAGAGTAACAAATGATGCTAGAGAAACAGAAATGGATGAGAACCTTGAGCAAGTCAGTGGCATTATTGGAAATCTTCGTCATATGGCACTTGATATGGGCAATGAGATTGACACACAAAATCGCCAGATTGACAGGATCATGGAGAAGGCTGATTCCAACAAAGCCAGGATTGATGAGGCCAATAAGCATGCCACAAAGATGCTGGGCAGTGGTTAGATCCAGCGGTGGGGCTCCTGTCTCCCGATACTGTCCCACAAGACAGTACATTCATGCTTTTACCATGGTATTTACCTACTAGGTTCGCACACATGCACATATCAGCCTCCCTTGTAAATGTTGTCCTGTGTAGTATGTCAGCTTTCCAAAAAGAAAAATATATACTTGTAATTATTTCTTTTCTAGATATCTTCCTTTCCAAAGGTTGTATATAGTGAAATAGCTCACTATGCCATTCGTTTTCATTTGTTCGTTTCATTTTTTAACGTTTTTTTTTTTAATGATTTTCGCTGAATGACAACAATGTAGGAATGTTAAACGTGCTGTTTACCTTGAACTTCACAGTATTGTTCTTGTAAAATTGTGACATTCCAGAGAGCTACTGCCATTCTTTTGTTTTTTTCCTTCTCTATGTCATGATAACTAAGCTGTCGAACTTGCTGTCCTCGGTTCTTCCTCGCAAACATCCGTTGTTATAATTTCATGATTAGAACGTGGAACTATATAACTATATTAAGCATTGCACTACCAGTGATGTGAGTTATGCATTGATGCATGAAAACAAATAGACATTTAGATGCCAAAATAAGAAGACCTTACACTGGCAGTAGCACATCAACTAAAAAGCATGCTGAGTATTTGGACACTGTTGGGACTATGTTAAACCAGCAAGTTTGCTGTAGTGCCACTTTTCTGTCAATATATCGATATATTTGAACATAATCATGCTTTTTTAATTTATTTTTTTTTGTTCGTTGGTTTGTTTCAAAGGGCAGACTTGGCACACACCTCTAGCAAAAATATATATAAAGCTTTTTTTGTTTTGGTTTTTTTTTTTTTTTGCTGGTAATATATAAAAAATAAAAAAATAAAAAACACAAGTTTTAAGGTTGTAATATAGGGTTTGGATACTGTTTTTGAGGATCCTCTTTTGGAGGAGATGACTACAATCTAAATGGTACAATGACATGTAATTTTTATAAAGACTGAGTCGTTAGCCTCTTAAATCCCCACGTGGTTTATTTTATGTACTGTTCTCTGTCGCTTACCTAGAGCTATGCACACCAAAATCGCTGAGATGTTTAAGTAGATTATAAATTAAGACAATATCTTAAATGACTGAAATCTAGATCCAACTGTGATATCAATATCATTGCAGCATGTACTATTAAATTCCTTATGTCTCCTGTCAGTTTGTGAAGTGATTGACATTTTGTAGCTAGTTTAAAACAATTAAAAAAATATAAATCTGAAAAAAAAAAAAAAAAAA	Refseq >NM_001087041|Xenopus laevis synaptosomal-associated protein, 25kDa (snap25), mRNA GACTCGAGGAACGGTGCTTCTTGCCTCCCTGCGAAAAAAAACTGCCTTCAGATAAGATTGTAGAGTAGCCTTAGGACCTGCTTACGCCCTACTCACGGTAGGGAATTTTTTAAGGGAGCCCCCTTATAAGTAACACATTCAGACATCATGGCAGACGACGCTGATATGCGCAATGAGCTGGAGGAGATGCAAAGGCGTGCAGATCAGCTGGCTGATGAGTCACTGGAGAGCACCCGCCGTATGCTGCAGTATGTTGAAGGGAGTAAAGATGCTGGTATCAGGACTTTGGTTATGTTGGATGAGCAAGGAGAACAACTGGAACGCATCGAGGAGGGAATGGAACAAATCAATAAGGACATGAAAGAAGCAGAAAAGAATTTGACGGACCTAGGAAAATTCTGTGGTCTATGTGTCTGTCCATGTAACAAGCTTAAATCCAGTGATGCTTACAAAAAGGCTTGGGGCAATAACCAAGATGGGGTTGTAGCAAGCCAACCTGCTCGTGTTGTGGATGAGCGTGAGCAGATGGCCATAAGTGGAGGCTTTGTCCGTAGAGTAACAAATGATGCCAGAGAAACAGAAATGGATGAAAACCTCGAGCAAGTCGGTGGCATTATTGGAAATCTTCGTCACATGGCCCTTGATATGGGCAATGAGATTGATACACAAAATCGCCAGATTGACAGGATCATGGAGAAGGCTGATTCCAACAAGGCCAGGATTGATGAGGCCAACAAACATGCCACAAAGATGCTGGGCAGTGGTTAGATCCAATGGTGGAGCTTCTGTATGATACTGTCCCTCAAGACAATGCTTTCATGCTTTTACCATGGTATTTACCTACTAGGTTTGCACACATGCACATATCAGCCTCCCTTGTAAATGTTGTCCTGTGTAGTATGTCAGCTTTCCTAAAAGAAAAATATATACTTGTAATTATTTCTTTTCTAGATATCTTCCTTTCCAAAGGATGTATATAGTGAAATAGCTCACTATGCCATTTGGATTTTGTTTGTTTGTTTGTTTTTGTTCATTTCATTTTTTAATTTTTTTGTAAAAAGATTTCTGTTGAATGACAACGATGTTGGAATGTTAAACGTGCTGTTTATCTTGAACTTCACAGTATTGTTCTTGTAAAATTGTGACATTCCAGAGAGCTACCGCCATTCTTTCTTTTTTCTTCTCTATGTCATGATAATTACGCTGTGGAACTTGCTGTCCTTGGTTCTTCCTTGCAAACATCTGTTGTTATAATTTCATTAAAACGTGGACCTATATAACTATATTAAGCATTGCACTACAAGTGATGTGTGTTATGCATTGATGCATGAAAACAAATAGACATTTAGATGCCTAAATAATAAGACCTTACACCGGCAGTAGCACATCAACTAAAAAGCATGCTGAGTATTTGGACACTGTTGGGACTGTGTTAAACCAGCAAGTTTGCTGTAGTGCCACATTTATGTCAATGTATAGATATATTTGAACATAATTATGCGTTTTTGTTTGTTTATTTGTTTATTTGTTTGTTACAAAGGGCAGACTTGGCACATACTTCTAGCAAAAATATATATAATGCTTTTTTTTTGCTGGTAATATATAAAAAATTAAAAAAAAAAAAAAA
Protein		Refseq >NP_001016501|synaptosomal-associated protein, 25kDa [Xenopus (Silurana) tropicalis] MADDADMRNELEEMQRRADQLADESLESTRRMLQYVEGSKDAGIRTLVMLDEQGEQLERIEEGMEQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFVRRVTNDARETEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKARIDEANKHATKMLGSG	Refseq >NP_001080510|synaptosomal-associated protein, 25kDa [Xenopus laevis] MADDADMRNELEEMQRRADQLADESLESTRRMLQYVEGSKDAGIRTLVMLDEQGEQLERIEEGMEQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFVRRVTNDARETEMDENLEQVGGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKARIDEANKHATKMLGSG

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.15491 [+] Str.80260	Xl.71917
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	SNAP25
mouse		MGI	Snap25	All(7) Targeted, knock Out(2) Targeted, other(3) Chemically Induced(1)
zebrafish		ZFIN ZFIN	snap25a snap25b

Publications
First:		Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels. [EMBO J 1996]
Most recent:		CaV2.1 (P/Q channel) interaction with synaptic proteins is essential for depolarization-evoked release. [Channels (Austin) 2010]
		View All Papers

Functional Ontologies
GO: Molecular:		transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:
EC:
KOG:		[U] SNAP-25 (synaptosome-associated protein) component of SNARE complex

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.15491.1.S1_at	Xl.13623.1.S1_at [+] Xl.13623.1.S2_at
Affymetrix 2.0			Xl2.13623.1.S1_at [+] Xl2.13623.1.S2_at

Symbol legend[+]

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