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Summary Expression Gene Literature (3) GO Terms (27) Nucleotides (52) Proteins (21) Interactants (8) Wiki
XB-GENEPAGE-949930
Gene Symbol:
clcn4

Gene Name:
chloride channel, voltage-sensitive 4

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Cl- channel CLC-3 and related proteins (CLC superfamily)

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
non-syndromic X-linked intellectual disability

OMIM:
RAYNAUD-CLAES SYNDROME; MRXSRC

External Links:
 
Xenbase Gene ID XB-GENE-949931 XB-GENE-6252319 XB-GENE-17337884
Gene Symbol clcn4 clcn4.L clcn4.S
Chromosome Chr2 Scaffold366843
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 6.0
CDS Gene model
Entrez Gene 100145074
397880
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq  More.. RefSeq
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine clcn4 clcn4.L clcn4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards CLCN4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Clcn4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Clcn4 Ensembl
zebrafish
ZFIN, AGR clcn4 ZFIN Ensembl
chicken
GEISHA CLCN4 Ensembl
fruit fly
Publications
First A new region of conservation is defined between human and mouse X chromosomes., Genomics 1996  
Most Recent De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females., Mol Psychiatry 2018          
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 24 terms 6 terms 0 term
PANTHER clcn4
KEGG Pathways K05012 K05012
KOG [P] Cl- channel CLC-3 and related proteins (CLC superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks clcn4
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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