Gene Symbol: slc26a4 Gene Name: solute carrier family 26, member 4 Synonyms: pendrin, eva, pds, dfnb4, tdh2b Add Xenopus synonyms Gene Function: sulfate transporter Interactants: ptgds(10) , slc26a6(7) , slc26a3.1(3) , ca12(2) , cyp26a1(2) , foxi1(2) , slc26a1(2) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001113663|Xenopus (Silurana) tropicalis solute carrier family 26, member 4 (slc26a4), mRNA GCAAGGTCTATATAACCTGCTGTGTGTAAAGCCAAGGTTGCTGGGAACTATGGCAACAGGAAGAATGGATATCCCCAGCCCTGGCTACAACCAGTACCTGGTACACCGATCGGTCTACAATGAGCCAACCTTCCAGGATGATAATGAAAGAAAAGAGCGTGTTCAGAAAACTGTCCAGGACAGAATAAAAAAGAATTGCAGCTGTACATCAAAAAAGGCTTACTTTATAGTCAAGAAGTTTTTCCCTGTTCTGGATTGGTTGCCCAAATACAGATGGAAAGAATGGTTTGTTAATGATCTGATCTCCGGAGTCAGCACAGGTCTTGTTGGTACCTTGCAAGGATTGGCATTTGCATTACTTGCTGCAGTCCCTGTTGGATACGGTCTATATTCTTCTTTTTTCCCTATCTTGACATATTTTTTCCTGGGAACATCAAAACACATTTCTGTTGGACCGTTCCCAGTGGTCAGTTTGATGGTGGGATCAGTTGTTCTGTCAATTGCTCCAGATGAAAAGTTTGCAATATTAGGCAACGCCACAGGACTGAACAAAACCATAATAGACACAGTAGCAAGAGACGCAGCCAGAATTGCTGTTTCAGGAACACTCAGCTTTCTAATTGGAATTATACAGCTTGCACTTGGAATATTTCAAATTGGCTTCATTGTCAGATACTTGGCAGACCCTTTAGTTGGTGGGTTTACAACAGCTGCAGCCTTCCAAGTGTTTGTTTCACAATTTAAACTTGTGCTCAATGTCCCCACACAGAACTACAATGGAGTACTTTCTATCATATATACAATAAGAGATATCTTTATGAACATTCGGCTAACCAACATCGCTGATCTGATTGCTGGACTTCTAACATTTGTTGTTTGCGTTGTGGTGAAAGAAATAAATGATCGGTACAAACGCATCTTTCGGGTACCTATTCCCATAGAAGTTATTGTGACCATAGTAGCTACAGGGATTTCATATGGTGTCAATCTGCACGCAAAATATAATGCAGGGATTGTGGCAACAATTCCAAGTGGGTTTATACCACCCATGACACCAGATGTGAGCCTATTTTCACAAATAGGTAGTTCAGCATTTTCCATTGGAATTGTTGCCTATGCTGTAGCTGTGTCCGTGGGAAAAGTTTATGCCACAAAGCATAACTATGAAGTTGATGGAAATCAGGAGTTCATCGCCTTTGGAATAAGCAATCTGTTCGGCGGAGCATTTTCTTGCTTTTGTGCCACCACTGCCTTATCCCGTACAGCTGTCCAGGAAAGCACTGGAGGCAGAACACAGATTGCTGGGATTATATCAGCTGGTATTGTGTTAATTGCAATTGTGGCACTTGGCAGGCTGCTGGAACCCCTGCAAAAGTCAGTGCTTGCGGCCATTGTCATTGCCAATCTGAAGGGGATGTTTTGGCAAGTTTTTGATATACCTCGCTTGTGGAAACAGAACAAATGGGACTCAGCTATCTGGGTTTTTACCTGCATTGCATCAATCTTTCTGGGACTTGACTCAGGACTGTTAGCTGGCTTGTTGTTTGGATTAGCGACTATTCTTTTACGCGTTCAGTTCCCTTCATGTGGTGCTCTTGGCAATGTTCCTGGCACAGATATCTACAAAAATGTCAAAGAATACAAAAATCTCATAGAGCCAGAAGGAGTTAAAATAATTCGGCATACTAGTGGCATGTTTTATGGAAATATCGATGGGTTTAAAAATGCCATCAAATCAATTGTTGGATTTGATCCTGTGAAAGTTTATAACAAGAGAACAAAAGCACTGAGAAAAATACAAAAGCTTATTAAAAAAGGACAACTAAGATCAACGAAGAATGGCGTCATTAGCAACACAGGAACTGATAATGAAGGTTTTGAGCCTGATGAGGATGTTGAGGACCCAGAACAAGAAAATAATGGAGCAGTTCAAACAAAAGAAGTAGAAATCCAAGTAGACTGGAACTCAGAACTTCCTGTAAAAATATCTGTGCCAAAAGTCTCCATTCACAGCATTATTTTTGATTTTGGGCAAATCCATTTCATTGATGTGGTTGCAGTGAGATCTCTAAAAGTGATATTTAAAGAATTAAAGAGAATTGATGTGGAGCCATACATTGCAGCATGTGAAGATGGTGTTTTACAAAAGATGGGATCATGCCTTTTCTTTGACGAGATAATCAAACATGACATCTTCTTTTTGACCGTCCATGATGCTGTGCTTCATATAGAAAACTTAAGAAAGTTTTATGATGGTCATGATCCTCTCCTTGAAAAGATTTCACTCATGCAAGAATCTAAGGAACCACTGGAATTCACCACAATTGACCCAACAGACCAAGAACTGGATGCCCAGGAAGGGGCTCTTCGATCACTGGCACACTGAAGAAACACATCTGGGAGATTCATCAGGGATGGACATTATCATTCTTTGGGTTTAATAACGAGACATTCATCTGCTAGGATCATGCTATGCATGTGATAAAAATGTTGTTTATATTAATGAATTATATGATGGGTGACTCCTCAAAAACCTTCCAAACAGCATTATAAATGTGTAAAACAGTTAAACAACAAAATCAAGTGTCCATATAGTACTGGTTTAAAATGTACTTCCTTTCTGATAAGGACTGAACAGCCATTTAGAGCAGAAGTTGAGGTTTAAAGTATAATGAGCCTGGGTGATATGACATTGAAGTCAACAGATACCCATGATGATTGAGAGGTATTTCGATCTATGCATGTACCAGGACAAGAGAGGAGGAAAGGAATATGTTCAACAATCTGAAGAAAGAAAACATTAACACAAATAAAACTGAGTGTTGAGGAAAAGAACATTACTGTTACTGAAAAACTGAAGCCACAACATCAAAGGCTTTAGATACTTCTATGAAATAAGATAAGTGTAATTTAATAAATACATTTTGGCCTGAGTGCATCATTGAATGGTAAAACAATTACATACATTAAGCATCCTTTTAAGTCACACTATGTATATCAAAAATGAATGCATGGCTGTAAGCTATAGTCAATTTATAATTATAGATCTTTCTAAACTAAATTAATTCAGTAGGATCTGAGAAAAGAAATCTACATATTAATTGTACACAGTATATCCATTTTGAGGGTTTTCTATAAAGATTAATCATTTATCCTGTTTATCCTTTTTACATAAATCTGTGTATATCTGACTTTAGGCACTTTACAAAAGAATTCTAAATAAAGAACGTATGGGTAAACACTGAAAAAAAAAAAAAAAAAA	Refseq >NM_001095539|Xenopus laevis solute carrier family 26, member 4 a (slc26a4-a), mRNA GCACGCGGGGCACGAGGCTGGGAACTGTAATTTTTTCAGGAAGCATAGATGGCAACAGCAAGAATGGATATCCCCAGCCCTGGCTACAACCAATACCTGGTGCACAGATCAGTCTACTCTGAACCAACATTCCAAGAAGAAAATGAAAGAAAAGAGCCTGTTCGGAAAACTCTCCAGGACAGGGTGAAAAAGAATTGCAGCTGTACATCAAAAAAGGCTTTGTTTATAGTCAAGAAGTTTCTCCCTATTCTGAATTGGTTACCCAAATACAGATGGAAAGAATGGTTTTTAAGTGACCTGATCTCTGGAGTCAGCACAGGTCTTGTTGGTACCTTGCAAGGCCTGGCATTTGCATTGCTTGCTGCAGTCCCTGTTGGATATGGCCTCTACTCTTCTTTTTTCCCTATCTTGACTTATTTTTTCCTGGGAACATCAAAACACATTTCTGTGGGACCATTCCCAGTGGTCAGTTTGATGGTGGGATCAGTTGTTCTGTCTATTGCTCCAGATGAAAAATTTGCAATATTAGGCAACTCTACAGGACTGAACAAAACAATAATAGACACAGTAGCAAGAGATGCAGCCAGAGTTGCCGTTTCAGGAACACTCAGCTTTCTAATTGGAATTATACAGCTTGCACTTGGCGTATTTCAAATTGGCTTTATTATCAGATATTTGGCAGATCCATTAGTTGGTGGTTTTACTACAGCTGCAGCCTTCCAAGTGTTTGTTTCACAATTCAAACTAGTGCTCAATGTCCCCACAAAGAACTACAACGGAGTACTCTCTATCATATATACAATAATAGATATCTTTACCAACATTGCGAAAACCAACATTGCTGATCTGATTGCTGGACTTCTAACATTTGTTGTTTGCGTTGTGGTGAAAGAAATAAATGATCGATACAAACGCATCTTTCGGGTACCTATTCCTATAGAAGTAATTGTGACCATAGTAGCTACAGGGATTTCATATGGCGTCAATCTGGAAAAGAAATATAATGCAGGGATTGTGAAGACAATTCCAACTGGATTCATACCACCTATGACACCAGACGTGAGCCTCTTCTCACAAATAGGTAGTTCAGCATTTTCCATCGGTATTGTTGCCTATGCTGTAGCTGTGTCTGTGGGAAAAGTTTATGCTACAAAGCACAACTATGAAGTTGATGGAAATCAGGAGTTCATTGCCTTTGGAATAAGCAATCTATTCGGTGGAGTATTTTCTTGCTTTTGTGCCACCACGGCCCTATCACGTACAGCTATCCAGGAAAGCACTGGAGGCAAAACACAGATTGCTGGGATTATCTCAGCTGGGATTGTGTTAATTGCAATTGTGGCACTTGGCAAGCTCCTTGAACCCCTTCAAAAGTCAGTGCTAGCGGCCATTGTCATTGCCAATCTGAAGGGGATGTTTTGGCAAGTTTTTGATGTACCTCGCTTATGGAAACAGAACAAATGGGACTCAGTTATCTGGGTTTTTACCTGCATTGCATCAATCCTTCTGGGACTTGATTTAGGACTGCTAGCTGGCTTGTTGTTTGGATTAGTGACTATTATTTTACGTGTTCAGTTCCCTTCATGTGGAGCTCTTGGTAGTGTTCCTGGCACAGACATTTACAAAAATGTCAAAGAATACAAAAATCTCATAGAGCCAGAAGGAGTTAAAATCATTCGCTATACAAGTGGTATGTTTTATGGAAATATCGACGGGTTTAAGAATGCCATCAAATCAATTGTTGGGTTTGATGCGGTGAAAGTTTATAACAAGAGAACAAAAGCACTGAGGAAAATACAAAAGCTTATTAAAAAAGGACAACTAAGATCAACAAAGAATGGCATTATTAGCAGCACAGGAGCAGATAATGAAGGTTATGAGCCTGATGATGATCCCGAGGACCCAGAACAAGAAAATAATGAAGCAGTTCAAACAAAAGAAGTAGAGATCCAAGTAGACTGGAACTCAGAACTTCCAATAAAAGTATCTGTGCCCAAAGTCTCCATTCACAGCATCATTTTTGATTTTGGGCAAATCCACTTCATTGATGTGGTTGCAGTGAGATCTCTTAAAGTGATATTTAAAGAATTTAAGAGAATTGATGTAGAGCCATACATTGCAGCATATGAAGATGGTGTTTTACAAAAAATGGAAAAATGCTTTTTCTTTGATGAGGTGATCAAACGAGACATCTTCTTTTTGACCGTCCATGATGCTGTGCTGCATATAGAGAACCTGAGAAAGTTCTATGATGGTCATGATCCTCTTCTTGAAAAGATTTCACTCATGCAAGAATCTAAGGAACCATTGGAGTTCACCACAACTGACCCAACAGACCAAGAACTGGATGCCCAGGAAGGGGCTCTCCGATCACTGGCACACTGAAGAAAGGCATCTGTAACACTCATTAGGGACAGTATCATCCTTTGGGTTCAATAACGAGACATTTGCTGTTTCATTAACATCTACTAATACCATGCTATGCATATGATAAAAATGTTATGAATGTTTATGAATTATATGATGGGCAACTCCTCAAAAACCTTCCAAACAGCATTTTAAATGTGTAAAACAGATAGACAACAAAACCAAGTGTCCTTATACTACTGGTTTTAAGCATCCTTCCTTTCTGATAAGGACTGAACAGCCATTTAGAGATTGAGGTTTAAAGTATAATGAGCCTAGGTGATATTGAAGTCAACAGATGTTATGATTGAGAGGTATTCCGATTTATGCACCTACCAGGACAAGAGAGGAGGAAAGGAATATGTGCAACATTCTAATGAATAAACATATAAACAAAAATAAAATTGAGTGTTGAGGCAAAGAACATGACTGTTACCCAAACATTTAAGCCACAACATCAAATTCTTCAAATTCTGTGAACTAAGATAAGTTTAATATAACAAATACATGTTGGCCTGACTGCCTCATTAAATGGCAAAATATTTACATAAATTAAGCATATTCATTTTAAGTCACAAGGGGGTTAGTTATTAAAATCCGAATGCCAAAATCTCCAAAAATTCTAGTTTTTTTTTTTTTTACTATAAAATCTGAATTTTTAGTGAAAAAAAAAAACAAACAAATTTTTCAAAATTTATTATACCCCGAGAATGGAAAAAGTCAGGATACGAAAATCCGGCATTTTAGACCTGTCGAGGTGGTATATATATATATATAAGTCAATTGCAGAGTTTCCTATAGTATTTGGAAATTTTCTCGCTGAAATTAGCCATAAAATTCTACTATTTTGGACTTTTTGGGCAAAAATCTGAAAAATTCAGGGTTTTTGGGAAAAACCCTTAAAAATCCAGCAATTTGGGGAAAACTCTGAAAAAAACATACGATTTGGATTTTCTCTAGATTTTGTTGAGTTTGTCCCCGATCCAATTAAATTGTGTTTTTTTATTAATAAATAAAGTCACAACATCAGATTTTTTTTTTGGTCAGACTTTTTTCATTTAAATCAGAAAAATTCTGATTTTGATAAATAATGCCCTAAGTGTAGCAAATATTAATATGTGGCTGTGAACTATAGTCAGTTTATTATAAGTATTTTACAAGTATAGATCAGTATAGCTCTATAGTATAAATCTTACTAAACTAAAGTAATTTAGTAGTATCTGTGAAAA
Protein		Refseq >NP_001107135|solute carrier family 26, member 4 [Xenopus (Silurana) tropicalis] MATGRMDIPSPGYNQYLVHRSVYNEPTFQDDNERKERVQKTVQDRIKKNCSCTSKKAYFIVKKFFPVLDWLPKYRWKEWFVNDLISGVSTGLVGTLQGLAFALLAAVPVGYGLYSSFFPILTYFFLGTSKHISVGPFPVVSLMVGSVVLSIAPDEKFAILGNATGLNKTIIDTVARDAARIAVSGTLSFLIGIIQLALGIFQIGFIVRYLADPLVGGFTTAAAFQVFVSQFKLVLNVPTQNYNGVLSIIYTIRDIFMNIRLTNIADLIAGLLTFVVCVVVKEINDRYKRIFRVPIPIEVIVTIVATGISYGVNLHAKYNAGIVATIPSGFIPPMTPDVSLFSQIGSSAFSIGIVAYAVAVSVGKVYATKHNYEVDGNQEFIAFGISNLFGGAFSCFCATTALSRTAVQESTGGRTQIAGIISAGIVLIAIVALGRLLEPLQKSVLAAIVIANLKGMFWQVFDIPRLWKQNKWDSAIWVFTCIASIFLGLDSGLLAGLLFGLATILLRVQFPSCGALGNVPGTDIYKNVKEYKNLIEPEGVKIIRHTSGMFYGNIDGFKNAIKSIVGFDPVKVYNKRTKALRKIQKLIKKGQLRSTKNGVISNTGTDNEGFEPDEDVEDPEQENNGAVQTKEVEIQVDWNSELPVKISVPKVSIHSIIFDFGQIHFIDVVAVRSLKVIFKELKRIDVEPYIAACEDGVLQKMGSCLFFDEIIKHDIFFLTVHDAVLHIENLRKFYDGHDPLLEKISLMQESKEPLEFTTIDPTDQELDAQEGALRSLAH	Refseq >NP_001089008|solute carrier family 26, member 4 [Xenopus laevis] MATARMDIPSPGYNQYLVHRSVYSEPTFQEENERKEPVRKTLQDRVKKNCSCTSKKALFIVKKFLPILNWLPKYRWKEWFLSDLISGVSTGLVGTLQGLAFALLAAVPVGYGLYSSFFPILTYFFLGTSKHISVGPFPVVSLMVGSVVLSIAPDEKFAILGNSTGLNKTIIDTVARDAARVAVSGTLSFLIGIIQLALGVFQIGFIIRYLADPLVGGFTTAAAFQVFVSQFKLVLNVPTKNYNGVLSIIYTIIDIFTNIAKTNIADLIAGLLTFVVCVVVKEINDRYKRIFRVPIPIEVIVTIVATGISYGVNLEKKYNAGIVKTIPTGFIPPMTPDVSLFSQIGSSAFSIGIVAYAVAVSVGKVYATKHNYEVDGNQEFIAFGISNLFGGVFSCFCATTALSRTAIQESTGGKTQIAGIISAGIVLIAIVALGKLLEPLQKSVLAAIVIANLKGMFWQVFDVPRLWKQNKWDSVIWVFTCIASILLGLDLGLLAGLLFGLVTIILRVQFPSCGALGSVPGTDIYKNVKEYKNLIEPEGVKIIRYTSGMFYGNIDGFKNAIKSIVGFDAVKVYNKRTKALRKIQKLIKKGQLRSTKNGIISSTGADNEGYEPDDDPEDPEQENNEAVQTKEVEIQVDWNSELPIKVSVPKVSIHSIIFDFGQIHFIDVVAVRSLKVIFKEFKRIDVEPYIAAYEDGVLQKMEKCFFFDEVIKRDIFFLTVHDAVLHIENLRKFYDGHDPLLEKISLMQESKEPLEFTTTDPTDQELDAQEGALRSLAH

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.55619 [+] Str.83895	Xl.14481
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		1 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	SLC26A4	OMIM:600791 OMIM:274600
mouse		MGI	Slc26a4	All(6) Targeted, knock Out(2) Spontaneous(1) Chemically Induced(1)
zebrafish		ZFIN	slc26a4

Publications
First:		Poorly selective cation channels in the apical membrane of A6 cells. [Pflugers Arch 1994]
Most recent:		Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease. [Dis Model Mech 2011]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		secondary active sulfate transmembrane transporter activity
Biological:		sulfate transport
Cellular Component:		membrane
EC:
KOG:		[P] Sulfate/bicarbonate/oxalate exchanger SAT-1 and related transporters (SLC26 family)

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.15488.1.S1_at
Affymetrix 2.0			Xl2.14481.1.S1_at

Symbol legend[+]

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