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XB-GENEPAGE-950934
Gene Symbol:
pam
Gene Name: peptidylglycine alpha-amidating monooxygenase
Synonyms:
pal
,
phm
,
pam-a
,
pam-b
,
AE-I
( Gene Function: Peptidylglycine alpha-amidating monooxygenase Protein Function
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Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated t...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-950935 | XB-GENE-950939 | XB-GENE-6252615 | |||||
Gene Symbol | pam | pam.L | pam.S | Chromosome | Chr1 | chr1L | chr1S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100170159
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379207
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397736
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | pam | pam.L | pam.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Peptide C-terminal alpha-amidating enzyme purified to homogeneity from Xenopus laevis skin., Biochem Biophys Res Commun 1986 |
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Most Recent |
A System for Assessing Dual Action Modulators of Glycine Transporters and Glycine Receptors., Biomolecules 2020 ![]() |
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All | View All Papers 2 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 35 terms | 7 terms | 7 terms | |||||
PANTHER | pam | |||||||
KEGG Pathways | K24006 | K24006 [+] | K18200 [+] | |||||
KOG |
[O] Peptidylglycine alpha-amidating monooxygenase
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | pam | |||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



