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Summary Expression Gene Literature (4) GO Terms (11) Nucleotides (308) Proteins (47) Interactants (445) Wiki
XB-GENEPAGE-951277
Gene Symbol:
hccs

Gene Name:
holocytochrome c synthase

Synonyms:
cchl , mcops7 , hccs-a , hccs-b ( Add synonyms , Nomenclature history )

Gene Function:
Holocytochrome c synthase/heme-lyase

Protein Function :
Links covalently the heme group to the apoprotein of cytochrome c.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
microphthalmia [+]

OMIM:
LINEAR SKIN DEFECTS WITH MULTIPLE CONGENITAL ANOMALIES 1; LSDMCA1

External Links:
 
Xenbase Gene ID XB-GENE-951278 XB-GENE-6253917 XB-GENE-951284
Gene Symbol hccs hccs.L hccs.S
Chromosome Chr04 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448226
380272
447038
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hccs hccs.L hccs.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HCCS OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hccs MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hccs Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR hccsb hccsa.1 ZFIN Ensembl
chicken
GEISHA HCCS Ensembl
fruit fly
worm
Publications
First HDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing., Oncogene 2005  
Most Recent GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery., Cell Rep 2020                            
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 4 terms 4 terms
PANTHER hccs
KEGG Pathways K01764 K01764 K01764
KOG [CO] Holocytochrome c synthase/heme-lyase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hccs
ORFs hccs ORF1 hccs.L ORF1 hccs.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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